[HTML][HTML] The food metabolome: a window over dietary exposure
The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With> 25,000 …
the digestion and biotransformation of foods and their constituents. With> 25,000 …
Post-selection inference
AK Kuchibhotla, JE Kolassa… - Annual Review of …, 2022 - annualreviews.org
We discuss inference after data exploration, with a particular focus on inference after model
or variable selection. We review three popular approaches to this problem: sample splitting …
or variable selection. We review three popular approaches to this problem: sample splitting …
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing
Hypothesis weighting improves the power of large-scale multiple testing. We describe
independent hypothesis weighting (IHW), a method that assigns weights using covariates …
independent hypothesis weighting (IHW), a method that assigns weights using covariates …
Exact post-selection inference, with application to the lasso
We develop a general approach to valid inference after model selection. At the core of our
framework is a result that characterizes the distribution of a post-selection estimator …
framework is a result that characterizes the distribution of a post-selection estimator …
Profiling cellular diversity in sponges informs animal cell type and nervous system evolution
JM Musser, KJ Schippers, M Nickel, G Mizzon… - Science, 2021 - science.org
The evolutionary origin of metazoan cell types such as neurons and muscles is not known.
Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous …
Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous …
Discovering the false discovery rate
Y Benjamini - Journal of the Royal Statistical Society Series B …, 2010 - academic.oup.com
I describe the background for the paper 'Controlling the false discovery rate: a new and
powerful approach to multiple comparisons' by Benjamini and Hochberg that was published …
powerful approach to multiple comparisons' by Benjamini and Hochberg that was published …
Statistical challenges of high-dimensional data
IM Johnstone, DM Titterington - … Transactions of the …, 2009 - royalsocietypublishing.org
Modern applications of statistical theory and methods can involve extremely large datasets,
often with huge numbers of measurements on each of a comparatively small number of …
often with huge numbers of measurements on each of a comparatively small number of …
Simultaneous and selective inference: Current successes and future challenges
Y Benjamini - Biometrical Journal, 2010 - Wiley Online Library
The previous decade can be viewed as a second golden for era Multiple Comparisons
research. I argue that much of the success stems from our being able to address real current …
research. I argue that much of the success stems from our being able to address real current …
Systems-level organization of yeast methylotrophic lifestyle
H Rußmayer, M Buchetics, C Gruber, M Valli… - BMC biology, 2015 - Springer
Background Some yeasts have evolved a methylotrophic lifestyle enabling them to utilize
the single carbon compound methanol as a carbon and energy source. Among them, Pichia …
the single carbon compound methanol as a carbon and energy source. Among them, Pichia …
Evolution of a minimal cell
RZ Moger-Reischer, JI Glass, KS Wise, L Sun… - Nature, 2023 - nature.com
Possessing only essential genes, a minimal cell can reveal mechanisms and processes that
are critical for the persistence and stability of life,. Here we report on how an engineered …
are critical for the persistence and stability of life,. Here we report on how an engineered …