Chiral amines are key structural motifs present in a wide variety of natural products, drugs,
and other biologically active compounds. During the past decade, significant advances have …

Transition-metal-catalysed asymmetric reductive amination (ARA) represents one of the
most straightforward methods to access chiral amines, which converts easily accessible …

Asymmetric reductive amination (ARA) of a prochiral carbonyl compound with an amine
using a H2/hydrogen surrogate is a concise and operationally simple method for the …

A ruthenium/C3-TunePhos catalytic system has been identified for highly efficient direct
reductive amination of simple ketones. The strategy makes use of ammonium acetate as the …

A borrowing‐hydrogen reaction between amines and alcohols is an atom‐economic way to
prepare alkylamines, ideally with water as the sole byproduct. Herein, nickel catalysts are …

An efficient cobalt‐catalyzed asymmetric hydrogenation of C= N bonds has been realized.
Chiral hydrazines were obtained in high yields and with excellent enantioselectivities (95 …

The asymmetric ruthenium-catalyzed reductive amination employing ammonia and
hydrogen to primary amines is described. Here we demonstrate the capability of our catalyst …

Direct asymmetric reductive amination is one of the most efficient methods for the
construction of chiral amines, in which the scope of the applicable amine coupling partners …

A highly efficient method for chemical modification of chitosan biopolymers by reductive
amination to yield N, N-dialkyl chitosan derivatives was developed. The use of 3, 6-O-di-tert …

We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones
and other ketimines with formic acid. Strongly donating bisphosphines must be used to …