Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …

Babies born small are at an increased risk of developing myriad adult diseases. While
growth restriction increases disease risk in all individuals, often a second hit is required to …

Lactation is a critical period during which maternal nutritional and environmental challenges
affect milk composition and, therefore, organ differentiation, structure, and function in …

Key points Uteroplacental insufficiency compromises maternal mammary development, milk
production and pup organ development; this is ameliorated by cross‐fostering, which …

Early epidemiology studies in humans have and continue to offer valuable insight into the
Developmental Origins of Health and Disease (DOHaD) hypothesis, which emphasises the …

Stressors during the fetal and postnatal period affect the growth and developmental
trajectories of offspring, causing lasting effects on physiologic regulatory systems. Here, we …

Low birth weight programs diseases in adulthood, including adverse bone health. These
diseases can have intergenerational and transgenerational origins, whereby transmission to …

Growth restriction programs adult bone deficits and increases the risk of obesity, which may
be exacerbated during pregnancy. We aimed to determine if high-fat feeding could …

Alcohol consumption in Australia is high and despite the NHMRC guidelines clearly
indicating that when pregnant or planning a pregnancy, not drinking is the safest option …