The human Y chromosome is intriguing not only because it harbours the master-switch gene
that determines gender but also because of its unusual evolutionary history. The Y …

Although sex is a fundamental component of eukaryotic reproduction, the genetic systems
that control sex determination are highly variable. In many organisms the presence of sex …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

The canonical model of sex-chromosome evolution predicts that, as recombination is
suppressed along sex chromosomes, gametologs will progressively differentiate, eventually …

Sex chromosomes have evolved many times in animals and studying these replicate
evolutionary “experiments” can help broaden our understanding of the general forces …

Teleost fishes, thanks to their rapid evolution of sex determination mechanisms, provide
remarkable opportunities to study the formation of sex chromosomes and the mechanisms …

Prevailing models of sex-chromosome evolution were largely inspired by the stable and
highly differentiated XY pairs of model organisms, such as those of mammals and flies …

Although the molecular mechanisms underlying many developmental events are conserved
across vertebrate taxa, the lability at the top of the sex‐determining (SD) cascade has been …

Triggers and biological processes controlling male or female gonadal differentiation vary in
vertebrates, with sex determination (SD) governed by environmental factors or simple to …

Recent studies have revealed a surprising diversity of sex chromosomes in vertebrates.
However, the detailed mechanism of their turnover is still elusive. To understand this …