miRNAs can affect intestinal epithelial barrier in inflammatory bowel disease

X Xiao, X Mao, D Chen, B Yu, J He, H Yan… - Frontiers in …, 2022 - frontiersin.org
The most obvious pathological characterization of inflammatory bowel disease (IBD) is
intestinal epithelium erosion and severe inflammation invasion. Micro-ribonucleic acids …

The role of MiRNA‐433 in malignant tumors of digestive tract as tumor suppressor

J Tang, J Chen, Y Wang, S Zhou - Cancer Reports, 2022 - Wiley Online Library
Background MicroRNAs (miRNAs) are a class of short non‐coding RNAs with a length of
approximate 22 nuclei acids that can be expressed both as an oncogene and tumor …

Long non-coding RNA MEG3 alleviated ulcerative colitis through upregulating miR-98-5p-sponged IL-10

Y Wang, N Wang, L Cui, Y Li, Z Cao, X Wu, Q Wang… - Inflammation, 2021 - Springer
Ulcerative colitis (UC) is a refractory chronic colitis disease with the particularly complex
cause. Recently, long noncoding RNAs (lncRNAs) have been reported to be related to the …

The role of telocytes and miR-21-5p in tumorigenicity and metastasis of breast cancer stem cells

S Babadag, Ö Altundag-Erdogan… - Molecular Biology …, 2024 - Springer
Background This study aims to investigate the roles of telocytes on the metastatic properties
of breast cancer stem cells (CSCs), and to re-evaluate the effect of miR-21-5p expression on …

Wu-Mei-Wan ameliorates murine ulcerative colitis by regulating macrophage polarization

S Yan, H Wei, R Jia, M Zhen, S Bao, W Wang… - Frontiers in …, 2022 - frontiersin.org
An increasing body of evidence shows that macrophages play an important role in the
pathogenesis of ulcerative colitis (UC). Macrophage polarization and changes in related …

Alterations in plasma miR-21, miR-590, miR-192 and miR-215 in idiopathic pulmonary fibrosis and their clinical importance

H Dirol, A Toylu, AC Ogus, A Cilli, O Ozbudak… - Molecular Biology …, 2022 - Springer
Background Many studies have revealed that microRNA (miRNA) molecules may take part
in idiopathic pulmonary fibrosis (IPF). But, the role of miRNAs in the development of IPF is …

PRMT1 modulates processing of asthma-related primary MicroRNAs (Pri-miRNAs) into mature miRNAs in lung epithelial cells

W Zhai, H Sun, Z Li, L Li, A Jin, Y Li, J Chen… - The Journal of …, 2021 - journals.aai.org
Abstract Protein arginine methyltransferase-1 (PRMT1) is an important epigenetic regulator
of cell function and contributes to inflammation and remodeling in asthma in a cell type …

[HTML][HTML] Myricetin and myricetrin alleviate liver and colon damage in a chronic colitis mice model: Effects on tight junction and intestinal microbiota

E Li, T Wang, R Zhou, Z Zhou, C Zhang, W Wu… - Journal of Functional …, 2021 - Elsevier
This study investigated the protective effects of myricetin (MYR) and myricetrin (MYRR) in
dextran sodium sulfate (DSS) induced liver and colon damage in mice. The results showed …

Protective effect of five-flavor sophora flavescens enteric-coated capsules on inflammatory bowel disease and its molecular mechanism

Y XIANG, B Jiang, S ZHONG, Y WU, J LIU… - Food Science and …, 2023 - SciELO Brasil
This study aims to investigate the effect of five-flavor sophora flavescens enteric-coated
capsules (FSEC) on TNF-α-induced inflammatory bowel disease and its molecular …

Fundamental transport mechanism of mucin-2 ER-to-Golgi trafficking identifies source of ER stress in inflammatory bowel disease

MAJ Morsink, LS Koch, S Hu, RK Weersma… - bioRxiv, 2024 - biorxiv.org
The intestinal mucous layer relies on mucin-2 secretion. While the mucin-2 secretory
pathway has been studied, endoplasmic reticulum (ER) to Golgi apparatus (Golgi) trafficking …