Oxidative stress, hormones, and effects of natural antioxidants on intestinal inflammation in inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal (GI) disorder
characterized by intestinal inflammation. The etiology of IBD is multifactorial and results from …
characterized by intestinal inflammation. The etiology of IBD is multifactorial and results from …
Canine chronic enteropathy—Current state-of-the-art and emerging concepts
AE Jergens, RM Heilmann - Frontiers in Veterinary Science, 2022 - frontiersin.org
Over the last decade, chronic inflammatory enteropathies (CIE) in dogs have received great
attention in the basic and clinical research arena. The 2010 ACVIM Consensus Statement …
attention in the basic and clinical research arena. The 2010 ACVIM Consensus Statement …
Stem cell-derived intestinal organoids: a novel modality for IBD
C Tian, M Yang, H Xu, M Zhu, NN Yue, Y Zhang… - Cell Death …, 2023 - nature.com
The organoids represent one of the greatest revolutions in the biomedical field in the past
decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly …
decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly …
Differential transcriptomic profiles following stimulation with lipopolysaccharide in intestinal organoids from dogs with inflammatory bowel disease and intestinal mast …
DK Sahoo, DC Borcherding, L Chandra, AE Jergens… - Cancers, 2022 - mdpi.com
Simple Summary Lipopolysaccharide (LPS) derived from intestinal bacteria is linked to long-
lasting inflammation that contributes to the development of intestinal cancer. While much …
lasting inflammation that contributes to the development of intestinal cancer. While much …
Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity
Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk
factors, chronic kidney disease, and the cardiovascular system. A growing body of literature …
factors, chronic kidney disease, and the cardiovascular system. A growing body of literature …
Canine intestinal organoids as a novel in vitro model of intestinal drug permeability: A proof-of-concept study
A key component of efforts to identify the biological and drug-specific aspects contributing to
therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal …
therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal …
Associations of inflammatory cytokines with inflammatory bowel disease: a Mendelian randomization study
Z Song, X Li, J Xie, F Han, N Wang, Y Hou… - Frontiers in …, 2024 - frontiersin.org
Objectives Previous studies have confirmed a link between specific inflammatory cytokines
and inflammatory bowel disease (IBD), but the causal relationship between them is not …
and inflammatory bowel disease (IBD), but the causal relationship between them is not …
Exploring the role of antioxidants in sepsis-associated oxidative stress: a comprehensive review
Sepsis is a potentially fatal condition characterized by organ dysfunction caused by an
imbalanced immune response to infection. Although an increased inflammatory response …
imbalanced immune response to infection. Although an increased inflammatory response …
Gut microbiome signatures of Yorkshire Terrier enteropathy during disease and remission
The role of the gut microbiome in developing Inflammatory Bowel Disease (IBD) in humans
and dogs has received attention in recent years. Evidence suggests that IBD is associated …
and dogs has received attention in recent years. Evidence suggests that IBD is associated …
The application of organoids in colorectal diseases
Y Liu, D Wang, Y Luan, B Tao, Q Li, Q Feng… - Frontiers in …, 2024 - frontiersin.org
Intestinal organoids are a three-dimensional cell culture model derived from colon or
pluripotent stem cells. Intestinal organoids constructed in vitro strongly mimic the colon …
pluripotent stem cells. Intestinal organoids constructed in vitro strongly mimic the colon …