[HTML][HTML] Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations

D Primorac, V Molnar, E Rod, Ž Jeleč, F Čukelj… - Genes, 2020 - mdpi.com
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

[HTML][HTML] NF-κB signaling pathways in osteoarthritic cartilage destruction

MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …

[HTML][HTML] Contribution of infrapatellar fat pad and synovial membrane to knee osteoarthritis pain

E Belluzzi, E Stocco, A Pozzuoli, M Granzotto… - BioMed research …, 2019 - hindawi.com
Osteoarthritis (OA) is the most common form of joint disease and a major cause of pain and
disability in the adult population. Interestingly, there are patients with symptomatic OA …

Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4/MyD88/NF‐κB signal pathway

Y Zhang, Y Zeng - Drug Development Research, 2019 - Wiley Online Library
Abstract Preclinical Research & Development Curcumin has been shown to possess a
series of beneficial effects, such as antiinflammatory, antioxidant, analgesic, and promoting …

Autologous minced cartilage implantation for treatment of chondral and osteochondral lesions in the knee joint: an overview

GM Salzmann, R Ossendorff, R Gilat, BJ Cole - Cartilage, 2021 - journals.sagepub.com
Cartilage defects in the knee are being diagnosed with increased frequency and are treated
with a variety of techniques. The aim of any cartilage repair procedure is to generate the …

[HTML][HTML] Blueberries improve pain, gait performance, and inflammation in individuals with symptomatic knee osteoarthritis

C Du, A Smith, M Avalos, S South, K Crabtree, W Wang… - Nutrients, 2019 - mdpi.com
Osteoarthritis (OA) is the most common joint disorder in the world and is the most frequent
cause of walking related disability among older adults in the US, which brings a significant …

[HTML][HTML] Intraarticular ligament degeneration is interrelated with cartilage and bone destruction in osteoarthritis

G Schulze-Tanzil - Cells, 2019 - mdpi.com
Osteoarthritis (OA) induces inflammation and degeneration of all joint components including
cartilage, joint capsule, bone and bone marrow, and ligaments. Particularly intraarticular …

[HTML][HTML] Characterization of the proinflammatory profile of synovial fluid-derived exosomes of patients with osteoarthritis

R Domenis, R Zanutel, F Caponnetto… - Mediators of …, 2017 - hindawi.com
The purpose of this study is to characterize synovial fluid-(SF-) derived exosomes of patients
with gonarthrosis comparing two methods of isolation and to investigate their immune …

[HTML][HTML] Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype

SJB Snelling, S Bas, GJ Puskas, SG Dakin, D Suva… - PloS one, 2017 - journals.plos.org
Purpose Osteoarthritis (OA) is a common and heterogeneous arthritic disorder. Patients
suffer pain and their joints are characterized by articular cartilage loss and osteophyte …

Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study

PA Gupte, SA Giramkar, SM Harke… - Journal of …, 2019 - Taylor & Francis
Purpose Osteoarthritis is the single most common cause of disability in older adults with an
estimated 10% to 15% prevalence in individuals above 60 years. The contemporary …