Extracellular vesicles in immunomodulation and tumor progression

C Marar, B Starich, D Wirtz - Nature immunology, 2021 - nature.com
Extracellular vesicles have emerged as prominent regulators of the immune response
during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a …

Cancer nanomedicine for combination cancer immunotherapy

J Nam, S Son, KS Park, W Zou, LD Shea… - Nature Reviews …, 2019 - nature.com
Cancer immunotherapy is revolutionizing oncology. However, dose-limiting toxicities and
low patient response rates remain major challenges in the clinic. Cancer nanomedicine in …

A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy

J Xu, J Lv, Q Zhuang, Z Yang, Z Cao, L Xu, P Pei… - Nature …, 2020 - nature.com
Cancer metastases and recurrence after surgical resection remain an important cause of
treatment failure. Here we demonstrate a general strategy to fabricate personalized …

Bioinspired and biomimetic delivery platforms for cancer vaccines

J Liu, SS Liew, J Wang, K Pu - Advanced Materials, 2022 - Wiley Online Library
Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …

Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy

Y Ding, Y Wang, Q Hu - Exploration, 2022 - Wiley Online Library
Immunotherapy strategies that use cell‐based delivery systems have sparked much interest
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …

Engineered nanoparticles for cancer vaccination and immunotherapy

ME Aikins, C Xu, JJ Moon - Accounts of chemical research, 2020 - ACS Publications
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …

Cell membrane coated nanocarriers-an efficient biomimetic platform for targeted therapy

P Dash, AM Piras, M Dash - Journal of controlled release, 2020 - Elsevier
Targeted therapy approaches have become the core of modern translational science and as
an intriguing field, it is the solution of the conventional drug delivery problems that were …

Biomimetic nanotechnology toward personalized vaccines

J Zhou, AV Kroll, M Holay, RH Fang… - Advanced …, 2020 - Wiley Online Library
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …

Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Emerging biomaterials for tumor immunotherapy

M Xiao, Q Tang, S Zeng, Q Yang, X Yang… - Biomaterials …, 2023 - spj.science.org
Background The immune system interacts with cancer cells in various intricate ways that can
protect the individual from overproliferation of cancer cells; however, these interactions can …