Functionalized DNA nanomaterials targeting toll‐like receptor 4 prevent bisphosphonate‐related osteonecrosis of the jaw via regulating mitochondrial homeostasis in …
T Zhang, H Ma, X Zhang, S Shi… - Advanced Functional …, 2023 - Wiley Online Library
Imbalance of macrophage polarization characterized by an increase in the percentage of
pro‐inflammatory M1 macrophages and a decrease in anti‐inflammatory M2 macrophages …
pro‐inflammatory M1 macrophages and a decrease in anti‐inflammatory M2 macrophages …
Directing toll-like receptor signaling in macrophages to enhance tumor immunotherapy
Q Zeng, CM Jewell - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Macrophages are unique targets because they naturally infiltrate
tumors.•Macrophages can exhibit tumor-supportive or anti-tumor phenotypes.•TLR signaling …
tumors.•Macrophages can exhibit tumor-supportive or anti-tumor phenotypes.•TLR signaling …
Zoledronic acid promotes TLR‐4‐mediated M1 macrophage polarization in bisphosphonate‐related osteonecrosis of the jaw
W Zhu, R Xu, J Du, Y Fu, S Li, P Zhang, L Liu… - The FASEB …, 2019 - Wiley Online Library
Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a detrimental side effect of the
long‐term administration of bisphosphonates. Although macrophages were reported to be …
long‐term administration of bisphosphonates. Although macrophages were reported to be …
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice
R Feng, JH Chen, CH Liu, FB Xia, Z Xiao, X Zhang… - Phytomedicine, 2019 - Elsevier
Background Excess alcohol exposure leads to alcoholic liver disease (ALD). Pueraria lobata
(PUE) and Silybum marianum (SIL) are two well-known hepatoprotective herbal remedies …
(PUE) and Silybum marianum (SIL) are two well-known hepatoprotective herbal remedies …
Shenjinhuoxue Mixture Attenuates Inflammation, Pain, and Cartilage Degeneration by Inhibiting TLR‐4 and NF‐κB Activation in Rats with Osteoarthritis: A Synergistic …
X Ma, C Hao, Z Zhang, H Jiang… - Oxidative Medicine …, 2021 - Wiley Online Library
Osteoarthritis (OA), a highly prevalent chronic joint disease, involves a complex network of
inflammatory mediators that not only triggers pain and cartilage degeneration but also …
inflammatory mediators that not only triggers pain and cartilage degeneration but also …
[HTML][HTML] Ginsenoside Rb3 exerts protective properties against cigarette smoke extract-induced cell injury by inhibiting the p38 MAPK/NF-κB and TGF-β1/VEGF …
M Wang, X Chen, W Jin, X Xu, X Li, L Sun - Biomedicine & …, 2018 - Elsevier
Cigarette smoke causes many adverse effects such as inflammation, oxidative stress, and
excessive accumulation of the extracellular matrix (ECM). Ginsenoside Rb3 has anti …
excessive accumulation of the extracellular matrix (ECM). Ginsenoside Rb3 has anti …
[HTML][HTML] Active polypeptides from Hirudo inhibit endothelial cell inflammation and macrophage foam cell formation by regulating the LOX-1/LXR-α/ABCA1 pathway
J Lu, X Chen, X Xu, J Liu, Z Zhang, M Wang, X Li… - Biomedicine & …, 2019 - Elsevier
Background and aims Hirudo is an important Chinese medicine that has been widely used
in patients with thrombosis-related diseases. We aimed to evaluate the protective effect and …
in patients with thrombosis-related diseases. We aimed to evaluate the protective effect and …
[HTML][HTML] Protective effect of pig brain polypeptides against corticosterone-induced oxidative stress, inflammatory response, and apoptosis in PC12 cells
W Jin, X Xu, X Chen, W Qi, J Lu, X Yan, D Zhao… - Biomedicine & …, 2019 - Elsevier
Objective Pig brain polypeptides (PBP), active polypeptides hydrolysate extracted from fresh
porcine brain tissue, has been shown to have neuroprotective effects in both in vitro and in …
porcine brain tissue, has been shown to have neuroprotective effects in both in vitro and in …
Autophagy ameliorates Pseudomonas aeruginosa‐infected diabetic wounds by regulating the toll‐like receptor 4/myeloid differentiation factor 88 pathway
X Ji, P Jin, P Yu, P Wang - Wound Repair and Regeneration, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are among the most common complications in patients with
diabetes and a leading cause of lower extremity amputation. DFUs are exacerbated by …
diabetes and a leading cause of lower extremity amputation. DFUs are exacerbated by …
Panax ginseng Total Protein Facilitates Recovery from Dexamethasone‐Induced Muscle Atrophy through the Activation of Glucose Consumption in C2C12 Myotubes
R Jiang, M Wang, L Shi, J Zhou, R Ma… - BioMed research …, 2019 - Wiley Online Library
Background. The clinical anti‐inflammatory drug dexamethasone (DEX) can cause many
side effects such as muscle atrophy for long‐term use. Muscle atrophy induced by DEX may …
side effects such as muscle atrophy for long‐term use. Muscle atrophy induced by DEX may …