Neutralizing antibodies for the prevention and treatment of COVID-19

L Du, Y Yang, X Zhang - Cellular & molecular immunology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) initiates the infection
process by binding to the viral cellular receptor angiotensin-converting enzyme 2 through …

Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson… - Science, 2021 - science.org
Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …

Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity

D Hagin, T Freund, M Navon, T Halperin, D Adir… - Journal of Allergy and …, 2021 - Elsevier
Background In mid-December 2020, Israel started a nationwide mass vaccination campaign
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …

Lower serologic response to COVID-19 mRNA vaccine in patients with inflammatory bowel diseases treated with anti-TNFα

H Edelman-Klapper, E Zittan, ABG Shitrit… - Gastroenterology, 2022 - Elsevier
Background & Aim Patients with inflammatory bowel diseases (IBD), specifically those
treated with anti–tumor necrosis factor (TNF) α biologics, are at high risk for vaccine …

A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies

F Ferrara, MF Erasmus, S D'Angelo… - Nature …, 2022 - nature.com
As a result of the SARS-CoV-2 pandemic numerous scientific groups have generated
antibodies against a single target: the CoV-2 spike antigen. This has provided an …

Therapeutic role of neutralizing antibody for the treatment against SARS-CoV-2 and its emerging variants: A clinical and pre-clinical perspective

M Bhattacharya, S Chatterjee, B Mallik, AR Sharma… - Vaccines, 2022 - mdpi.com
Since early 2020, the entire world has been facing a disastrous outbreak of the SARS-CoV-2
virus, with massive reporting of death and infections per day. Medical practitioners adopted …

Monkeypox infection elicits strong antibody and B cell response against A35R and H3L antigens

R Yefet, N Friedel, H Tamir, K Polonsky, M Mor… - IScience, 2023 - cell.com
Monkeypox virus (MPXV) resides in two forms; mature and enveloped, and depending on it,
distinct proteins are displayed on the viral surface. Here, we expressed two MPXV antigens …

A comprehensive review on immunogen and immune-response proteins of SARS-CoV-2 and their applications in prevention, diagnosis, and treatment of COVID-19

D Zhang, D Kukkar, KH Kim, P Bhatt - International Journal of Biological …, 2024 - Elsevier
Exposure to severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) prompts
humoral immune responses in the human body. As the auxiliary diagnosis of a current …

SARS-CoV-2 serology status detected by commercialized platforms distinguishes previous infection and vaccination adaptive immune responses

RT Suhandynata, NJ Bevins, JT Tran… - The journal of …, 2021 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has
infected over 110 million individuals and led to 2.5 million deaths worldwide. As more …