AnimalTFDB 4.0: a comprehensive animal transcription factor database updated with variation and expression annotations
WK Shen, SY Chen, ZQ Gan, YZ Zhang… - Nucleic acids …, 2023 - academic.oup.com
Transcription factors (TFs) are proteins that interact with specific DNA sequences to regulate
gene expression and play crucial roles in all kinds of biological processes. To keep up with …
gene expression and play crucial roles in all kinds of biological processes. To keep up with …
Transcription factor HIF1α promotes proliferation, migration, and invasion of cholangiocarcinoma via long noncoding RNA H19/microRNA-612/Bcl-2 axis
A Yu, L Zhao, Q Kang, J Li, K Chen, H Fu - Translational Research, 2020 - Elsevier
Cholangiocarcinoma, which is the most common invasive malignant tumor of the biliary tract,
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …
PU. 1 negatively regulates tumorigenesis in non-small-cell lung cancer
X Liu, M Xu, W Jia, Y Duan, J Ma, W Tai - Medical Oncology, 2023 - Springer
PU. 1 is a key transcription factor that modulates hematopoietic cell differentiation and is
involved in various physiological and pathological processes. PU. 1 has been described to …
involved in various physiological and pathological processes. PU. 1 has been described to …
Detection and independent validation of model-based quantitative transcriptional regulation relationships altered in lung cancers
Differential expressions of genes are widely evaluated for the diagnosis and prognosis
correlations with diseases. But limited studies investigate how transcriptional regulations are …
correlations with diseases. But limited studies investigate how transcriptional regulations are …
Identifying polymorphic cis-regulatory variants as risk markers for lung carcinogenesis and chemotherapy responses in tobacco smokers from eastern India
D Sengupta, P Mukhopadhyay, S Banerjee… - Scientific Reports, 2023 - nature.com
Aberrant expression of xenobiotic metabolism and DNA repair genes is critical to lung
cancer pathogenesis. This study aims to identify the cis-regulatory variants of the genes …
cancer pathogenesis. This study aims to identify the cis-regulatory variants of the genes …
Lung Cancer through Transcription Factors
KA Papavassiliou, N Anagnostopoulos… - International Journal of …, 2023 - mdpi.com
The body of knowledge on the molecular mechanisms that drive lung cancer, including non-
small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), is continuously growing …
small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), is continuously growing …
Synergistic antitumor activity of low-dose c-Met tyrosine kinase inhibitor and sorafenib on human non-small cell lung cancer cells
L Fu, L Guo, Y Zheng, Z Zhu, M Zhang… - Oncology …, 2018 - spandidos-publications.com
Sorafenib is a multikinase inhibitor that is frequently used to treat various types of malignant
tumors. However, it has been demonstrated that Sorafenib only has a moderate antitumor …
tumors. However, it has been demonstrated that Sorafenib only has a moderate antitumor …
Genetic Polymorphisms in Activating Transcription Factor 3 Binding Site and the Prognosis of Early-Stage Non-Small Cell Lung Cancer
Background: Activating transcription factor 3 (ATF3) plays a significant role in cancer
development and progression. We investigated the association between variants in …
development and progression. We investigated the association between variants in …