Metals and breast cancer

C Byrne, SD Divekar, GB Storchan, DA Parodi… - Journal of mammary …, 2013 - Springer
Metalloestrogens are metals that activate the estrogen receptor in the absence of estradiol.
The metalloestrogens fall into two subclasses: metal/metalloid anions and bivalent cationic …

Metallothioneins: historical review and state of knowledge

M Nordberg - Talanta, 1998 - Elsevier
The history of metallothionein (MT) research is reviewed. Various methods for isolation,
characterisation and quantification are evaluated. The role of MT in metal metabolism and …

Risk assessment of effects of cadmium on human health (IUPAC Technical Report)

GF Nordberg, A Bernard, GL Diamond… - Pure and Applied …, 2018 - degruyter.com
Abstract Chemistry and Human Health, Division VII of the International Union on Pure and
Applied Chemistry (IUPAC), provides guidance on risk assessment methodology and, as …

Kinetics and metabolism

GF Nordberg, T Kjellström, M Nordberg - Cadmium and health, 2019 - taylorfrancis.com
The kinetics and metabolism of cadmium include uptake, absorption, transport, distribution
within the body, excretion, and accumulation, as well as binding to proteins in tissues and …

Environmental exposure to cadmium and human birthweight

N Frery, C Nessmann, F Girard, J Lafond, T Moreau… - Toxicology, 1993 - Elsevier
Fetal toxicity of cadmium (Cd) is well documented in rodents. However, little information is
available regarding the human fetus. To investigate the effect of low levels of Cd on the …

Gestational Cd exposure in the CD-1 mouse induces sex-specific hepatic insulin insensitivity, obesity, and metabolic syndrome in adult female offspring

TW Jackson, GL Ryherd, CM Scheibly… - Toxicological …, 2020 - academic.oup.com
There is compelling evidence that developmental exposure to toxic metals increases risk for
obesity and obesity-related morbidity including cardiovascular disease and type 2 diabetes …

Toxicity of cadmium in the perfused human placenta

PJ Wier, RK Miller, D Maulik… - Toxicology and applied …, 1990 - Elsevier
Cadmium, a placental toxicant in rodents, was studied in the in vitro isolated dually perfused
human placental lobule for periods of up to 12 hr to determine if cadmium can also be toxic …

Cadmium absorption and its relationship to divalent metal transporter-1 in the pregnant rat

TM Leazer, Y Liu, CD Klaassen - Toxicology and applied pharmacology, 2002 - Elsevier
Increased intestinal absorption of essential nutrients is characteristic of pregnancy as the
maternal gastrointestinal tract undergoes physiological and biochemical changes to …

Acute cadmium exposure and ovarian steroidogenesis in cycling and pregnant rats

M Piasek, JW Laskey - Reproductive toxicology, 1994 - Elsevier
The purpose of this study was to evaluate the effect (s) of acute in vivo cadmium (Cd)
exposure on steroidogenesis in rat ovaries during different reproductive states. Sprague …

Toxicological significance of metallothionein

M Webb - Metallothionein II: Proceedings of the «Second …, 1987 - Springer
Abstract When in 1964, Piscator (1) proposed the hypothesis that the inducible synthesis of
metallothionein (MT) provided a protective, or detoxification mechanism at chronic exposure …