Hepatitis C virus RNA replication and assembly: living on the fat of the land
Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …
The multiples fates of the flavivirus RNA genome during pathogenesis
C Mazeaud, W Freppel, L Chatel-Chaix - Frontiers in genetics, 2018 - frontiersin.org
The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow
fever viruses) which constitute important public health concerns worldwide. For several of …
fever viruses) which constitute important public health concerns worldwide. For several of …
LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification
P Hou, S Meng, M Li, T Lin, S Chu, Z Li, J Zheng… - Journal of Experimental …, 2021 - Springer
Background Increasing studies have shown that long noncoding RNAs (lncRNAs) are
pivotal regulators participating in carcinogenic progression and tumor metastasis in …
pivotal regulators participating in carcinogenic progression and tumor metastasis in …
N6-methyladenosine in flaviviridae viral RNA genomes regulates infection
The RNA modification N6-methyladenosine (m 6 A) post-transcriptionally regulates RNA
function. The cellular machinery that controls m 6 A includes methyltransferases and …
function. The cellular machinery that controls m 6 A includes methyltransferases and …
The long non-coding RNA HIF1A-AS2 facilitates the maintenance of mesenchymal glioblastoma stem-like cells in hypoxic niches
Long non-coding RNAs (lncRNAs) have an undefined role in the pathobiology of
glioblastoma multiforme (GBM). These tumors are genetically and phenotypically …
glioblastoma multiforme (GBM). These tumors are genetically and phenotypically …
Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1
The genetic etiology of premature ovarian insufficiency (POI) has been well established to
date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this …
date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this …
Zika virus subverts stress granules to promote and restrict viral gene expression
G Bonenfant, N Williams, R Netzband… - Journal of …, 2019 - Am Soc Microbiol
Flaviviruses limit the cell stress response by preventing the formation of stress granules
(SGs) and modulate viral gene expression by subverting different proteins involved in the …
(SGs) and modulate viral gene expression by subverting different proteins involved in the …
RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity
F Valiente‐Echeverría, MA Hermoso… - Reviews in medical …, 2015 - Wiley Online Library
Summary Asp‐Glu‐Ala‐Asp (DEAD)‐box polypeptide 3, or DDX3, belongs to the DEAD‐box
family of ATP‐dependent RNA helicases and is known to play different roles in RNA …
family of ATP‐dependent RNA helicases and is known to play different roles in RNA …
A combined genetic-proteomic approach identifies residues within dengue virus NS4B critical for interaction with NS3 and viral replication
Dengue virus (DENV) infection causes the most prevalent arthropod-borne viral disease
worldwide. Approved vaccines are not available, and targets suitable for the development of …
worldwide. Approved vaccines are not available, and targets suitable for the development of …
Flaviviral RNAs: weapons and targets in the war between virus and host
K Bidet, MA Garcia-Blanco - Biochemical Journal, 2014 - portlandpress.com
Flaviviruses are a genus of (+) ssRNA (positive ssRNA) enveloped viruses that replicate in
the cytoplasm of cells of diverse species from arthropods to mammals. Many are important …
the cytoplasm of cells of diverse species from arthropods to mammals. Many are important …