Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update
S Liu, X Wen, X Zhang, S Mao - Expert opinion on drug delivery, 2023 - Taylor & Francis
Introduction Biomacromolecules have proven to be an attractive choice for treating diseases
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …
Biodegradable polymeric insulin microneedles–a design and materials perspective review
M Starlin Chellathurai, S Mahmood… - Drug Delivery, 2024 - Taylor & Francis
Microneedle (MN) delivery devices are more accepted by people than regular traditional
needle injections (eg vaccination) due to their simplicity and adaptability. Thus, patients of …
needle injections (eg vaccination) due to their simplicity and adaptability. Thus, patients of …
Materials and structure of polysaccharide-based delivery carriers for oral insulin: A review
X Wang, H Sun, T Mu - Carbohydrate Polymers, 2024 - Elsevier
Diabetes mellitus is a chronic metabolic disease that affects> 500 million patients worldwide.
Subcutaneous injection of insulin is the most effective treatment at present. However, regular …
Subcutaneous injection of insulin is the most effective treatment at present. However, regular …
β-Glucan and fatty acid based mucoadhesive carrier for gastrointestinal tract specific local and sustained drug delivery
The oral route is considered the most convenient route of drug administration for both
systemic and local delivery. Besides stability and transportation, another unmet but …
systemic and local delivery. Besides stability and transportation, another unmet but …
[HTML][HTML] Chinese herb pollen derived micromotors as active oral drug delivery system for gastric ulcer treatment
L Cai, C Zhao, X Cao, M Lu, N Li, Y Luo, Y Wang… - Bioactive Materials, 2024 - Elsevier
Considerable efforts have been devoted to treating gastric ulcers. Attempts in this field tend
to develop drug delivery systems with prolonged gastric retention time. Herein, we develop …
to develop drug delivery systems with prolonged gastric retention time. Herein, we develop …
[HTML][HTML] Emerging frontiers in drug delivery with special focus on novel techniques for targeted therapies
L Yu, S Liu, S Jia, F Xu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The management and treatment of disease are achieved via the use of pharmacologically
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
Untethered shape-changing devices in the gastrointestinal tract
Introduction Advances in microfabrication, automation, and computer engineering seek to
revolutionize small-scale devices and machines. Emerging trends in medicine point to smart …
revolutionize small-scale devices and machines. Emerging trends in medicine point to smart …
Gastrointestinal Permeation Enhancers Beyond Sodium Caprate and SNAC‐What is Coming Next?
M Bohley, JC Leroux - Advanced Science, 2024 - Wiley Online Library
Oral peptide delivery is trending again. Among the possible reasons are the recent
approvals of two oral peptide formulations, which represent a huge stride in the field. For the …
approvals of two oral peptide formulations, which represent a huge stride in the field. For the …
More Than Metal–Organic Frameworks: Intestinal Villi‐Inspired Device as a Therapeutic Platform for Oral Enzyme Delivery
X Qi, K Liu, Q Chen, Y Deng - Advanced Functional Materials, 2024 - Wiley Online Library
Macromolecules are fragile when orally administered. An intestinal villi‐inspired metal–
organic frameworks (MOFs)‐based smart pill with multiple advantages is developed to offer …
organic frameworks (MOFs)‐based smart pill with multiple advantages is developed to offer …
Designing self-triggered micro/milli devices for gastrointestinal tract drug delivery
LJ Cai, Y Wang, Z Luo, J Wang, H Ren… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Self-triggered micro-/milli-devices (STMDs), which are artificial devices capable
of responding to the surrounding environment and transferring external energy into kinetic …
of responding to the surrounding environment and transferring external energy into kinetic …