To investigate whether the tumor suppressor gene PTEN affects the activity of the androgen
receptor (AR), we monitored the expression of the apoptotic gene HA-Bax (inserted in an …

Stem cells/progenitors are being discovered in a growing number of adult tissues. They
have been hypothesized for a long time to exist in the pituitary, especially because this …

The transition to motherhood results in a number of hormonal, neurological and behavioral
changes necessary to ensure offspring survival. However, little attention has been paid to …

We studied the role of androgens in antler growth. In particular, we investigated whether the
onset of antler regrowth is triggered by a short-term pulse of testosterone and if low levels of …

Prolactin (PRL) is essential for a number of developmental events in the mammary gland.
Work with PRL and PRL receptor knockout mice has shown that PRL indirectly regulates …

Prolactin releasing peptide (PrRP) was originally isolated as an endogenous hypothalamic
ligand for the hGR3 orphan receptor. It has been shown to release prolactin from dispersed …

We investigated how maternal melatonin is regulated in pregnant rats. To examine the
involvement of the conceptus (fetus and placenta) in serum melatonin concentrations, the …

Maternal energy metabolism undergoes a singular adaptation during lactation that allows for
the caloric enrichment of milk. Changes in the mammary gland, changes in the white …

Transcription of the prolactin (PRL) gene has been reported to be activated by a nuclear
factor, Pit-1. However, the precise molecular mechanisms of the Pit-1-mediated PRL gene …

This manuscript proposes that melanin-concentrating hormone (MCH) in the medial preoptic
area (MPOA) is an neurochemical signal evolved to trigger the declining process of maternal …