In recent years, metabolic syndromes (MetSs), including diabetes mellitus, dyslipidemia, and
cardiovascular diseases, have become a common health problem in both developed and …

Hypertension impacts negatively on the quality of life of sufferers, and complications
associated with uncontrolled hypertension are life-threatening. Hence, many research efforts …

Spexin is a novel peptide implicated in obesity and energy homeostasis. The objective of the
current study was to evaluate the effect of spexin on blood pressure, insulin resistance, and …

Nonalcoholic fatty liver disease (NAFLD) is due to the excessive lipid accumulation within
hepatocytes. Metabolic nuclear receptors (MNRs) play great roles in lipid homeostasis. We …

Peroxisome proliferator-activator receptor (PPAR) γ is a nuclear hormone receptor that
regulates glucose homeostasis, lipid metabolism, and adipocyte function. It has been shown …

Background: Atherosclerosis is a medical urgency manifesting at the onset of
hypercholesterolemia and is associated with aging. Activation of PPARγ (peroxisome …

Aims/hypothesis The metabolic syndrome is a cluster of risk correlates that can progress to
type 2 diabetes. The present study aims to evaluate a novel molecule with a dual action …

The activation of the renin-angiotensin system (RAS) induced by increased angiotensin II
(AngII) levels has been implicated in muscle atrophy, which is involved in the pathogenesis …

RhoBTB proteins constitute a subfamily of atypical Rho GTPases represented in mammals
by RhoBTB1, RhoBTB2, and RhoBTB3. Their characteristic feature is a carboxyl terminal …

Polyphenol extracts derived from gastrointestinal digestates of buckwheat (Fagopyrum Mill)
were studied for their intestinal transport and lipid-lowering effects in Caco-2/HepG2 …