Abstract tRNAs, nexus molecules between mRNAs and proteins, have a central role in
translation. Recent discoveries have revealed unprecedented complexity of tRNA …

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

Quantitative measurement of transcription rates in live cells is important for revealing
mechanisms of transcriptional regulation. This is particularly challenging when measuring …

Purpose The m5C RNA methylation regulators are closely related to tumor proliferation,
occurrence, and metastasis. This study aimed to investigate the gene expression …

The ribosome is the enzymatic macromolecular machine responsible for protein synthesis.
The rates of protein synthesis are primarily dependent on translational efficiency and …

The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …

Increased proliferation and elevated levels of protein synthesis are characteristics of
transformed and tumor cells. Though components of the translation machinery are often …

The microbiota plays essential roles in health and disease, in both the intestine and the
extra-intestine. Dysbiosis of the gut microbiota causes dysfunction in the intestine, which …

In the extensive network of interdependent biochemical processes required for cell growth
and division, there is mounting evidence that ribosomal DNA transcription by RNA …

We examined the microRNA (miRNA) expression profile of 40 prostatectomy specimens
from stage T2a/b, early relapse and non-relapse cancer patients, to better understand the …