Depression in young people

A Thapar, O Eyre, V Patel, D Brent - The Lancet, 2022 - thelancet.com
Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …

Autism spectrum disorder: a review

T Hirota, BH King - Jama, 2023 - jamanetwork.com
Importance Autism spectrum disorder (ASD), characterized by deficits in social
communication and the presence of restricted, repetitive behaviors or interests, is a …

[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder

SV Faraone, T Banaschewski, D Coghill… - … & biobehavioral reviews, 2021 - Elsevier
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …

The Hierarchical Taxonomy of Psychopathology (HiTOP): A quantitative nosology based on consensus of evidence

R Kotov, RF Krueger, D Watson… - Annual review of …, 2021 - annualreviews.org
Traditional diagnostic systems went beyond empirical evidence on the structure of mental
health. Consequently, these diagnoses do not depict psychopathology accurately, and their …

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

N Mullins, AJ Forstner, KS O'Connell, B Coombes… - Nature …, 2021 - nature.com
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

R Karlsson Linnér, TT Mallard, PB Barr… - Nature …, 2021 - nature.com
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …

The contributions of rare inherited and polygenic risk to ASD in multiplex families

M Cirnigliaro, TS Chang, SA Arteaga… - Proceedings of the …, 2023 - National Acad Sciences
Autism spectrum disorder (ASD) has a complex genetic architecture involving contributions
from both de novo and inherited variation. Few studies have been designed to address the …

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - Nature …, 2023 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …

The genetic basis of major depressive disorder

J Flint - Molecular psychiatry, 2023 - nature.com
The genetic dissection of major depressive disorder (MDD) ranks as one of the success
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …

Elevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals

V Warrier, DM Greenberg, E Weir… - Nature …, 2020 - nature.com
It is unclear whether transgender and gender-diverse individuals have elevated rates of
autism diagnosis or traits related to autism compared to cisgender individuals in large non …