Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
Glutathione synthesis
SC Lu - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: Glutathione (GSH) is present in all mammalian tissues as the most
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …
Curcumin attenuates oxidative stress in RAW264. 7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway
X Lin, D Bai, Z Wei, Y Zhang, Y Huang, H Deng… - PloS one, 2019 - journals.plos.org
Large-scale breeding environments often lead to oxidative stress. Macrophages play an
important role in the immune system and are vulnerable to reactive oxygen species (ROS) …
important role in the immune system and are vulnerable to reactive oxygen species (ROS) …
Glutathione: overview of its protective roles, measurement, and biosynthesis
This review is the introduction to a special issue concerning, glutathione (GSH), the most
abundant low molecular weight thiol compound synthesized in cells. GSH plays critical roles …
abundant low molecular weight thiol compound synthesized in cells. GSH plays critical roles …
Regulation of glutathione synthesis
SC Lu - Molecular aspects of medicine, 2009 - Elsevier
Glutathione (GSH) is a ubiquitous intracellular peptide with diverse functions that include
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …
Scientific and medical aspects of ozone therapy. State of the art
VA Bocci - Archives of medical research, 2006 - Elsevier
The aim of this review is to dispel misconceptions and skepticism regarding ozone therapy
and to clarify the biochemical and pharmacological mechanisms of action of ozone …
and to clarify the biochemical and pharmacological mechanisms of action of ozone …
The ozone paradox: ozone is a strong oxidant as well as a medical drug
V Bocci, E Borrelli, V Travagli… - Medicinal research …, 2009 - Wiley Online Library
After five decades characterized by empiricism and several pitfalls, some of the basic
mechanisms of action of ozone in pulmonary toxicology and in medicine have been clarified …
mechanisms of action of ozone in pulmonary toxicology and in medicine have been clarified …
Role of oxidative stress in ocular diseases: a balancing act
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
Antioxidants and HNE in redox homeostasis
W Łuczaj, A Gęgotek, E Skrzydlewska - Free Radical Biology and Medicine, 2017 - Elsevier
Under physiological conditions, cells are in a stable state known as redox homeostasis,
which is maintained by the balance between continuous ROS/RNS generation and several …
which is maintained by the balance between continuous ROS/RNS generation and several …
Glutathione synthesis and its role in redox signaling
H Zhang, HJ Forman - Seminars in cell & developmental biology, 2012 - Elsevier
Glutathione (GSH) is the most abundant antioxidant and a major detoxification agent in cells.
It is synthesized through two-enzyme reaction catalyzed by glutamate cysteine ligase and …
It is synthesized through two-enzyme reaction catalyzed by glutamate cysteine ligase and …