Pre-determination of sex in pigs by application of CRISPR/Cas system for genome editing

S Kurtz, B Petersen - Theriogenology, 2019 - Elsevier
In livestock industries, one sex is usually preferred because of the impact on the production
(eg milk from cows, eggs from laying hens). Furthermore, in pig production, the male-specific …

Recent genetic advances on boar taint reduction as an alternative to castration: a review

DAS Duarte, M Schroyen, RR Mota… - Journal of Applied …, 2021 - Springer
Boar taint is an unpleasant odor in male pig meat, mainly caused by androstenone, skatole,
and indole, which are deposited in the fat tissue. Piglet castration is the most common …

Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs

S Kurtz, A Lucas-Hahn… - Proceedings of the …, 2021 - National Acad Sciences
The sex-determining region on the Y chromosome (SRY) is thought to be the central genetic
element of male sex development in mammals. Pathogenic modifications within the SRY …

Novel copy number variation of the KLF3 gene is associated with growth traits in beef cattle

JW Xu, L Zheng, LJ Li, Y Yao, H Hua, SZ Yang, YF Wen… - Gene, 2019 - Elsevier
Copy number variation (CNV) related to complex traits, such as disease and quantitative
phenotype, is considered an important and wealthy source of genetic and phenotypic …

Association between polymorphisms in the SOX9 region and canine disorder of sex development (78,XX; SRY-negative) revisited in a multibreed case-control study

J Nowacka-Woszuk, I Szczerbal, M Stachowiak… - PLoS …, 2019 - journals.plos.org
Testicular or ovotesticular disorders of sex development (DSD) in individuals with female
karyotype (XX) lacking the SRY gene has been observed in several mammalian species …

XX/XY chimerism in internal genitalia of a virilized heifer

I Szczerbal, J Nowacka-Woszuk, M Stachowiak… - Animals, 2022 - mdpi.com
Simple Summary Freemartinism is the most common type of disorder of sex development
(DSD) in heifers; it is caused by the formation of placental anastomoses between …

Genomic structural diversity in Criollo Argentino horses: Analysis of copy number variations

CM Corbi-Botto, H Morales-Durand, ME Zappa… - Gene, 2019 - Elsevier
Copy number variation (CNV) has been proved to be widespread in human, animal and
plant genomes. Together with single nucleotide polymorphisms (SNPs), CVNs play a key …

Copy number variation of the CCDC39 gene is associated with growth traits in Chinese cattle

L Hu, J Yu, R Huang, P Yang, Z Zhang… - Veterinary Medicine …, 2022 - Wiley Online Library
Background Copy number variation (CNV) has become an essential part of genetic
structural variation. Coiled‐coil domain containing 39 (CCDC39) is a gene that related to the …

[HTML][HTML] Genetic disorders of sex development in cats: An update

I Szczerbal, M Switonski - Animal reproduction science, 2020 - Elsevier
Disorders of sex development (DSD) are rarely reported in cats, but this does not mean
these occurrences are an insignificant reproductive and health problem in this species. The …

[HTML][HTML] Whole genome sequencing identifies a missense polymorphism in PADI6 associated with testicular/ovotesticular XX disorder of sex development in dogs

J Nowacka-Woszuk, M Stachowiak, I Szczerbal… - Genomics, 2022 - Elsevier
Disorders of sex development (DSDs) are congenital malformations defined as
discrepancies between sex chromosomes and phenotypical sex. Testicular or ovotesticular …