The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …

Certain bacteria constitute a threat to humans due to their ability to escape host defenses as
they easily develop drug resistance. Bacteria are classified into gram-positive and gram …

The eukaryotic cortical actin cytoskeleton creates specific lipid domains, including lipid rafts,
which determine the distribution of many membrane proteins. Here we show that the …

Biological membranes are composed of many molecular species of lipids and proteins.
These molecules do not mix ideally. In the plane of the membrane components are …

Characterizing atomic details of membrane binding of peripheral membrane proteins by
molecular dynamics (MD) has been significantly hindered by the slow dynamics of …

Background Membrane-bound intracellular organelles have characteristic shapes attributed
to different local membrane curvatures, and these attributes are conserved across species …

The domains are the structural and functional units of proteins. With the avalanche of protein
sequences generated in the postgenomic age, it is highly desired to develop effective …

Phase separation in lipid bilayers that include negatively charged lipids is examined
experimentally. We observed phase-separated structures and determined the membrane …

Several biologically important peripheral (eg, myristoylated alanine-rich C kinase substrate)
and integral (eg, the epidermal growth factor receptor) membrane proteins contain clusters …

Cytokines, lymphocytes, platelets and several biomolecules have long been implicated in
the pathology of rheumatoid arthritis (RA), and the influences of antibody production and …