Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris: a review
Z Yang, Z Zhang - Biotechnology advances, 2018 - Elsevier
Pichia pastoris has been recognized as one of the most industrially important hosts for
heterologous protein production. Despite its high protein productivity, the optimization of P …
heterologous protein production. Despite its high protein productivity, the optimization of P …
Making recombinant proteins in filamentous fungi-are we expecting too much?
H Nevalainen, R Peterson - Frontiers in microbiology, 2014 - frontiersin.org
Hosts used for the production of recombinant proteins are typically high-protein secreting
mutant strains that have been selected for a specific purpose, such as efficient production of …
mutant strains that have been selected for a specific purpose, such as efficient production of …
A Systematic Review of the Potential of Pichia pastoris (Komagataella phaffii) as an Alternative Host for Biologics Production
VE Vijayakumar, K Venkataraman - Molecular Biotechnology, 2024 - Springer
The methylotrophic yeast Pichia pastoris is garnering interest as a chassis cell factory for the
manufacture of recombinant proteins because it effectively satisfies the requirements of both …
manufacture of recombinant proteins because it effectively satisfies the requirements of both …
The advent of plant cells in bioreactors
F Verdú-Navarro, JA Moreno-Cid, J Weiss… - Frontiers in Plant …, 2023 - frontiersin.org
Ever since agriculture started, plants have been bred to obtain better yields, better fruits, or
sustainable products under uncertain biotic and abiotic conditions. However, a new way to …
sustainable products under uncertain biotic and abiotic conditions. However, a new way to …
Cellular and molecular effects of yeast probiotics on cancer
The cancer is one of the main causes of human deaths worldwide. The exact mechanisms of
initiation and progression of malignancies are not clear yet, but there is a common …
initiation and progression of malignancies are not clear yet, but there is a common …
The microalga Dunaliella and its applications: a review
M Barbosa, LG Inácio, C Afonso, P Maranhão - Applied Phycology, 2023 - Taylor & Francis
Green microalgae in the genus Dunaliella have become increasingly important in
biotechnology and industry. The high adaptability of Dunaliella to high salinity, as well as its …
biotechnology and industry. The high adaptability of Dunaliella to high salinity, as well as its …
Interferon-based biopharmaceuticals: Overview on the production, purification, and formulation
The advent of biopharmaceuticals in modern medicine brought enormous benefits to the
treatment of numerous human diseases and improved the well-being of many people …
treatment of numerous human diseases and improved the well-being of many people …
The α-mating factor secretion signals and endogenous signal peptides for recombinant protein secretion in Komagataella phaffii
C Zou, L Lu, S Wang, C Zhang, X Chen, Y Lin… - … for Biofuels and …, 2022 - Springer
Abstract Background The budding yeast Komagataella phaffii (Pichia pastoris) is widely
employed to secrete proteins of academic and industrial interest. For secretory proteins …
employed to secrete proteins of academic and industrial interest. For secretory proteins …
Organic wastes as feedstocks for non-conventional yeast-based bioprocesses
Non-conventional yeasts are efficient cell factories for the synthesis of value-added
compounds such as recombinant proteins, intracellular metabolites, and/or metabolic by …
compounds such as recombinant proteins, intracellular metabolites, and/or metabolic by …
Comparative genome‐scale analysis of Pichia pastoris variants informs selection of an optimal base strain
JR Brady, CA Whittaker, MC Tan… - Biotechnology and …, 2020 - Wiley Online Library
Komagataella phaffii, also known as Pichia pastoris, is a common host for the production of
biologics and enzymes, due to fast growth, high productivity, and advancements in host …
biologics and enzymes, due to fast growth, high productivity, and advancements in host …