The oxidation of lipids has long been a topic of interest in biological and food sciences, and
the fundamental principles of non-enzymatic free radical attack on phospholipids are well …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Background—Acute kidney injury (AKI) after cardiac surgery is a major health issue. Lacking
effective therapies, risk factor modification may offer a means of preventing this complication …

Aims Very few data exist on the occurrence of acute kidney injury (AKI) associated with
transcatheter aortic valve implantation (TAVI). The objectives of the present study were (i) to …

As the red cell emerges from the bone marrow, it loses its nucleus, ribosomes, and
mitochondria and therefore all capacity for protein synthesis. However, because of the high …

Hemoglobin has functions besides carrying oxygen to the tissues, and regulates vascular
tone and inflammation via a redox couple with methemoglobin. Hemoglobin has iron in the …

Sickle cell disease and β-thalassaemia are inherited haemoglobinopathies resulting in
structural and quantitative changes in the β-globin chain. These changes lead to instability …

Acute kidney injury (AKI) is a serious and common complication of major surgery. This
narrative review focuses on the relationship between perioperative red blood cell …

Heme (iron protoporphyrin IX) exists as prosthetic group in several hemoproteins, which
include respiration cytochromes, gas sensors, P450 enzymes (CYPs), catalases …

Significance: The physiological mechanism (s) for recognition and removal of red blood cells
(RBCs) from circulation after 120 days of its lifespan is not fully understood. Many of the …