Superoxide anion chemistry—Its role at the core of the innate immunity

CMC Andrés, JM Pérez de la Lastra… - International journal of …, 2023 - mdpi.com
Classically, superoxide anion O2•− and reactive oxygen species ROS play a dual role. At
the physiological balance level, they are a by-product of O2 reduction, necessary for cell …

Superoxide radicals in the execution of cell death

J Fujii, T Homma, T Osaki - Antioxidants, 2022 - mdpi.com
Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

Possible mechanisms of oxidative stress-induced skin cellular senescence, inflammation, and cancer and the therapeutic potential of plant polyphenols

HM Liu, MY Cheng, MH Xun, ZW Zhao… - International Journal of …, 2023 - mdpi.com
As the greatest defense organ of the body, the skin is exposed to endogenous and external
stressors that produce reactive oxygen species (ROS). When the antioxidant system of the …

Phytochemical Composition of Different Botanical Parts of Morus Species, Health Benefits and Application in Food Industry

AR Memete, AV Timar, AN Vuscan, F Miere, AC Venter… - Plants, 2022 - mdpi.com
In recent years, mulberry has acquired a special importance due to its phytochemical
composition and its beneficial effects on human health, including antioxidant, anticancer …

The Dsup coordinates grain development and abiotic stress in rice

C Ye, J Guo, X Zhou, D Chen, J Liu, X Peng… - Plant Physiology and …, 2023 - Elsevier
DNA damage is a serious threat to all living organisms and may be induced by
environmental stressors. Previous studies have revealed that the tardigrade (Ramazzotius …

A 7-hydroxy 4-methylcoumarin enhances melanogenesis in B16-F10 melanoma cells

T Kim, KB Kim, CG Hyun - Molecules, 2023 - mdpi.com
The objectives of this study were to investigate the melanogenetic potentials of the naturally
occurring 7-hydroxy coumarin derivatives 7-hydroxy 5, 6-dimethoxycoumarin (7H-5, 6DM), 7 …

Free radicals and obesity-related chronic inflammation contrasted by antioxidants: A new perspective in coronary artery disease

C Caiati, A Stanca, ME Lepera - Metabolites, 2023 - mdpi.com
We are surrounded by factors called free radicals (FR), which attach to the molecules our
body is made of, first among them the endothelium. Even though FR are to a certain extent a …

Systemic Oxidative Stress Parameters in Skin Cancer Patients and Patients with Benign Lesions

E Karampinis, PM Nechalioti, KE Georgopoulou… - Stresses, 2023 - mdpi.com
Oxidative stress is caused by an imbalance between the production and subsequent
accumulation of reactive oxygen species (ROS) in cells and tissues and the capacity of a …

Screening of benzophenone ultraviolet absorbers with high-efficiency light absorption capacity, low-permeability and low-toxicity by 3D-QSAR model

J Xiao, Y Li - Journal of Molecular Liquids, 2022 - Elsevier
In this study, the synthetical index method was used to calculate the comprehensive effect
value (CV) of ultraviolet (UV) absorption capacity, skin permeability, and planarian toxicity of …

Hepatocellular carcinoma antibodies preferably identify nitro-oxidative-DNA lesions induced by 4-Chloro-orthophenylenediamine and DEANO

S Khan, A Ali, MS Warsi, S Waris, A Raza, SA Ali… - Scientific Reports, 2024 - nature.com
The widespread use of oxidative hair colouring cosmetics threatens public health.
Phenylenediamine derivatives serve as the main pigment in permanent hair colours. They …