Mitochondria as potential targets in Alzheimer disease therapy: an update
G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …
affects mostly the elderly population. At the moment, no effective treatments are available in …
Cyclodextrins, natural compounds, and plant bioactives—a nutritional perspective
S Wüpper, K Lüersen, G Rimbach - Biomolecules, 2021 - mdpi.com
Cyclodextrins (CDs) are a group of cyclic oligosaccharides produced from starch or starch
derivatives. They contain six (αCD), seven (βCD), eight (γCD), or more glucopyranose …
derivatives. They contain six (αCD), seven (βCD), eight (γCD), or more glucopyranose …
Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies
Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …
Mitochondrial dysfunctions: a red thread across neurodegenerative diseases
Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …
Potential role of tocotrienols on non-communicable diseases: a review of current evidence
Tocotrienol (T3) is a subfamily of vitamin E known for its wide array of medicinal properties.
This review aimed to summarize the health benefits of T3, particularly in prevention or …
This review aimed to summarize the health benefits of T3, particularly in prevention or …
[HTML][HTML] Targeting mitochondrial bioenergetics as a promising therapeutic strategy in metabolic and neurodegenerative diseases
Mitochondria are the organelles that generate energy for the cells and act as biosynthetic
and bioenergetic factories, vital for normal cell functioning and human health. Mitochondrial …
and bioenergetic factories, vital for normal cell functioning and human health. Mitochondrial …
Physiological and pathological functions of neuronal hemoglobin: a key underappreciated protein in Parkinson's disease
R Zheng, Y Yan, J Pu, B Zhang - International Journal of Molecular …, 2022 - mdpi.com
The expression of Hemoglobin (Hb) is not restricted to erythrocytes but is also present in
neurons. Hb is selectively enriched in vulnerable mesencephalic dopaminergic neurons of …
neurons. Hb is selectively enriched in vulnerable mesencephalic dopaminergic neurons of …
Testosterone upregulates the expression of mitochondrial ND1 and ND4 and alleviates the oxidative damage to the nigrostriatal dopaminergic system in …
W Yan, Y Kang, X Ji, S Li, Y Li, G Zhang… - Oxidative medicine …, 2017 - Wiley Online Library
Testosterone deficiency, as a potential risk factor for aging and aging‐related
neurodegenerative disorders, might induce mitochondrial dysfunction and facilitate the …
neurodegenerative disorders, might induce mitochondrial dysfunction and facilitate the …
A review on the relationship between tocotrienol and Alzheimer disease
KY Chin, SS Tay - Nutrients, 2018 - mdpi.com
Alzheimer's disease (AD) is plaguing the aging population worldwide due to its tremendous
health care and socioeconomic burden. Current treatment of AD only offers symptomatic …
health care and socioeconomic burden. Current treatment of AD only offers symptomatic …
[HTML][HTML] Mitochondria research and neurodegenerative diseases: On the track to understanding the biological world of high complexity
From the simple unicellular eukaryote to the highly complex multicellular organism like
Human, mitochondrion emerges as a ubiquitous player to ensure the organism's …
Human, mitochondrion emerges as a ubiquitous player to ensure the organism's …