Fasudil loaded PLGA microspheres as potential intravitreal depot formulation for glaucoma therapy

R Mietzner, C Kade, F Froemel, D Pauly, WD Stamer… - Pharmaceutics, 2020 - mdpi.com
Rho-associated protein kinase (ROCK) inhibitors allow for causative glaucoma therapy.
Unfortunately, topically applied ROCK inhibitors suffer from high incidence of hyperemia and …

Biomechanical Characterization of Retinal Pigment Epitheliums Derived from hPSCs Using Atomic Force Microscopy

E Herardot, M Liboz, G Lamour, M Malo… - Stem Cell Reviews and …, 2024 - Springer
The retinal pigment epithelium (RPE), a multifunctional cell monolayer located at the back of
the eye, plays a crucial role in the survival and homeostasis of photoreceptors. Dysfunction …

Scleral remodeling in early adulthood: the role of FGF-2

Y Qin, T Liu, Z Zhang, S Xing, L Gong, Y Ni - Scientific Reports, 2023 - nature.com
Emmetropization, a natural process of ocular elongation, is closely associated with scleral
remodeling. The Fibroblast growth factor-2 (FGF-2) was reported involved in scleral …

Conditionally reprogrammed asthmatic bronchial epithelial cells express lower FOXJ1 at terminal differentiation and lower IFNs following RV-A1 infection

PC Veerati, KS Nichol, JM Read… - … of Physiology-Lung …, 2022 - journals.physiology.org
Primary bronchial epithelial cells (pBECs) obtained from donors have limited proliferation
capacity. Recently, conditional reprogramming (CR) technique has overcome this and has …

Human iPS cell derived RPE strips for secure delivery of graft cells at a target place with minimal surgical invasion

M Nishida, Y Tanaka, Y Tanaka, S Amaya, N Tanaka… - Scientific Reports, 2021 - nature.com
Several clinical studies have been conducted into the practicality and safety of regenerative
therapy using hESC/iPSC-retinal pigment epithelium (RPE) as a treatment for the diseases …

[HTML][HTML] Enhancing the engraftment of human induced pluripotent stem cell-derived cardiomyocytes via a transient inhibition of Rho kinase activity

M Zhao, Y Tang, PJ Ernst, A Kahn-Krell… - Journal of visualized …, 2019 - ncbi.nlm.nih.gov
A crucial factor in improving cellular therapy effectiveness for myocardial regeneration is to
safely and efficiently increase the cell engraftment rate. Y-27632 is a highly potent inhibitor …

ANLN 缺失后Hela 细胞的力学特性与骨架蛋白变化分析

徐丽萌, 罗文宇, 张书伟, 王立 - 中国组织工程研究, 2020 - cjter.com
ANLN缺失后Hela细胞的力学特性与骨架蛋白变化分析 Page 1 《中国组织工程研究》 Chinese
Journal of Tissue Engineering Research 文章编号:2095-4344(2020)01-00087-06 87 www.CRTER.org …

[HTML][HTML] Transient rho-associated coiled-coil containing kinase (ROCK) inhibition on human retinal pigment epithelium results in persistent Rho/ROCK downregulation

S Kitahata, H Ichikawa, Y Tanaka, T Inoue… - … and Biophysics Reports, 2020 - Elsevier
Retinal pigment epithelium (RPE) cells is the outermost layer of the retina and RPE
dysfunction is a key factor in the disease pathogenesis of age-related macular degeneration …

[PDF][PDF] 抑制视网膜色素上皮细胞发生上皮-间充质转化的研究进展

李摇铎, 沈摇涵, 袁松涛, 刘庆淮 - Guoji Yanke Zazhi (Int Eye Sci), 2018 - core.ac.uk
抑制视网膜色素上皮细胞发生上皮-间充质转化的研究进展 Page 1 ·文献综述· 抑制视网膜色素上皮
细胞发生上皮-间充质转化的研究 进展 李摇铎,沈摇涵,袁松涛,刘庆淮 基金项目:国家重点研发计划 …

Mechanical properties and cytoskeletal protein changes after ANLN deficiency

L Xu, W Luo, S Zhang, L Wang - Chinese Journal of Tissue Engineering …, 2020 - cjter.com
BACKGROUND: To date, ANLN has definite roles in altering cell shape, regulating cell-cell
junction integrity in interphase and stabilizing actomyosin contractile rings in cytokinesis, but …