Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease

B Zingales, DC Bartholomeu - Memórias do instituto oswaldo cruz, 2022 - SciELO Brasil
Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

Chagas disease in people with HIV: a narrative review

EH Clark, C Bern - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Many questions remain unanswered regarding the epidemiology, pathophysiology,
diagnosis, treatment, and monitoring of Trypanosoma cruzi infection in people with HIV …

Chagas disease in immunocompromised patients

EH Clark, LA Messenger, JD Whitman… - Clinical Microbiology …, 2024 - Am Soc Microbiol
As Chagas disease remains prevalent in the Americas, it is important that healthcare
professionals and researchers are aware of the screening, diagnosis, monitoring, and …

The expression of immune response genes in patients with chronic Chagas disease is shifted toward the levels observed in healthy subjects as a result of treatment …

I Gómez, A Egui, G Palacios, B Carrilero… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Chagas disease, caused by the Trypanosoma cruzi parasite infection, is a
potentially life-threatening neglected tropical disease with a worldwide distribution. During …

[HTML][HTML] Candidate SNP Markers Significantly Altering the Affinity of the TATA-Binding Protein for the Promoters of Human Genes Associated with Primary Open-Angle …

K Zolotareva, PA Dotsenko, N Podkolodnyy… - International Journal of …, 2024 - mdpi.com
Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition
leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol …

Narrowing the Relationship between Human CCR5 Gene Polymorphisms and Chagas Disease: Systematic Review and Meta-Analysis

JM Ferreira, BRC Santos, EL Moura, ACM Santos… - Life, 2023 - mdpi.com
Our aim was to carry out a qualitative and quantitative synthesis of the influence of CCR5
genetic variants on Chagas disease (CD) through a systematic review. A total of 1197 …

Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease

ACB de Lima, VG Mendes, RR Ferreira… - Memórias do Instituto …, 2023 - SciELO Brasil
BACKGROUND A positive Trypanosoma cruzi polymerase chain reaction (PCR) is
associated with a worse prognosis in patients with chronic Chagas disease (CD) …

[HTML][HTML] Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac …

A Cooley, KJ Rayford, A Arun, F Villalta, MF Lima… - Immune …, 2022 - ncbi.nlm.nih.gov
Trypanosoma cruzi, the etiological agent of Chagas disease, is an intracellular protozoan
parasite, which is now present in most industrialized countries. About 40% of T. cruzi …

Trypanosoma cruzi Pathogenesis: Dysregulation of Gene Expression and Cellular Signaling in Heart and Colon Cells During Early Phase of Infection

KJM Rayford - 2024 - search.proquest.com
Trypanosoma cruzi, the causative agent of Chagas Disease, causes severe morbidity,
mortality, and economic burden worldwide. Due to globalization, the parasite is now present …

Genética e epidemiologia da degeneração macular relacionada à idade: avaliação da variante rs1143627 (–31G> A) do gene IL1β e análise do perfil epidemiológico …

LSM Muniz - 2023 - bdtd.uerj.br
RESUMO MUNIZ, Lana Sayuri Makita. Genética e epidemiologia da degeneração macular
relacionada à idade: avaliação da variante rs1143627 (–31G> A) do gene IL1β e análise do …