Developing neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …

Serotonin (5-HT) shapes brain networks during development and modulates a wide
spectrum of essential neuronal functions ranging from perception and cognitive appraisal to …

The ability to culture and maintain postnatal mouse hippocampal and cortical neurons is
highly advantageous, particularly for studies on genetically engineered mouse models. Here …

Neurons use local protein synthesis to support their morphological complexity, which
requires independent control across multiple subcellular compartments up to the level of …

The molecular diversification of cell surface molecules has long been postulated to impart
specific surface identities on neuronal cell types. The existence of unique cell surface …

Cadherins are a superfamily of cell surface glycoproteins whose ectodomains contain
multiple repeats of β-sandwich extracellular cadherin (EC) domains that adopt a similar fold …

This paper describes the design and synthesis of a photostable, far-red to near-infrared
(NIR) platform for optical voltage sensing. We developed a new, sulfonated silicon …

We describe an engineered family of highly antigenic molecules based on GFP-like
fluorescent proteins. These molecules contain numerous copies of peptide epitopes and …

In development, wound healing, and cancer metastasis, vertebrate cells move through 3D
interstitial matrix, responding to chemical and physical guidance cues. Protrusion at the cell …

Collagen fibrils are the major tensile element in vertebrate tissues, in which they occur as
ordered bundles in the extracellular matrix. Abnormal fibril assembly and organization …