Tumor microenvironment: Challenges and opportunities in targeting metastasis of triple negative breast cancer
KGK Deepak, R Vempati, GP Nagaraju… - Pharmacological …, 2020 - Elsevier
Triple negative breast cancer (TNBC) is most aggressive subtype of breast cancers with high
probability of metastasis as well as lack of specific targets and targeted therapeutics. TNBC …
probability of metastasis as well as lack of specific targets and targeted therapeutics. TNBC …
Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …
Triple negative breast cancer treatment options and limitations: future outlook
O Obidiro, G Battogtokh, EO Akala - Pharmaceutics, 2023 - mdpi.com
Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER),
progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The …
progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The …
Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence
NM Almansour - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen,
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
Large-scale genomic studies have identified multiple somatic aberrations in breast cancer,
including copy number alterations and point mutations. Still, identifying causal variants and …
including copy number alterations and point mutations. Still, identifying causal variants and …
[HTML][HTML] Targeted therapies in breast cancer: New challenges to fight against resistance
V Masoud, G Pagès - World journal of clinical oncology, 2017 - ncbi.nlm.nih.gov
Breast cancer is the most common type of cancer found in women and today represents a
significant challenge to public health. With the latest breakthroughs in molecular biology and …
significant challenge to public health. With the latest breakthroughs in molecular biology and …
Perspectives on triple-negative breast cancer: current treatment strategies, unmet needs, and potential targets for future therapies
GK Gupta, AL Collier, D Lee, RA Hoefer, V Zheleva… - Cancers, 2020 - mdpi.com
Triple-negative breast cancer (TNBC), characterized by the absence or low expression of
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
Expression and function of the epidermal growth factor receptor in physiology and disease
J Chen, F Zeng, SJ Forrester, S Eguchi… - Physiological …, 2016 - journals.physiology.org
The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …
Notch signaling activation as a hallmark for triplenegative breast cancer subtype
MV Giuli, E Giuliani, I Screpanti, D Bellavia… - Journal of …, 2019 - Wiley Online Library
Triplenegative breast cancer (TNBC) is a subgroup of 15%20% of diagnosed breast
cancer patients. It is generally considered to be the most difficult breast cancer subtype to …
cancer patients. It is generally considered to be the most difficult breast cancer subtype to …
Challenge to overcome current limitations of cell-penetrating peptides
The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …