[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …
several human cancers, including breast cancer (BC), as strong evidence has been found …
Principles of miRNA–mRNA interactions: beyond sequence complementarity
F Afonso-Grunz, S Müller - Cellular and Molecular Life Sciences, 2015 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene
expression by altering the translation efficiency and/or stability of targeted mRNAs. In …
expression by altering the translation efficiency and/or stability of targeted mRNAs. In …
[HTML][HTML] Analysis of microRNA-target interactions across diverse cancer types
A Jacobsen, J Silber, G Harinath, JT Huse… - Nature structural & …, 2013 - nature.com
Little is known about the extent to which individual microRNAs (miRNAs) regulate common
processes of tumor biology across diverse cancer types. Using molecular profiles of> 3,000 …
processes of tumor biology across diverse cancer types. Using molecular profiles of> 3,000 …
Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function
PV Nazarov, SE Reinsbach, A Muller… - Nucleic acids …, 2013 - academic.oup.com
MicroRNAs (miRNAs) are ubiquitously expressed small non-coding RNAs that, in most
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …
[HTML][HTML] Global population-specific variation in miRNA associated with cancer risk and clinical biomarkers
RA Rawlings-Goss, MC Campbell, SA Tishkoff - BMC medical genomics, 2014 - Springer
Background MiRNA expression profiling is being actively investigated as a clinical
biomarker and diagnostic tool to detect multiple cancer types and stages as well as other …
biomarker and diagnostic tool to detect multiple cancer types and stages as well as other …
Statistical methods in integrative genomics
Statistical methods in integrative genomics aim to answer important biology questions by
jointly analyzing multiple types of genomic data (vertical integration) or aggregating the …
jointly analyzing multiple types of genomic data (vertical integration) or aggregating the …
[HTML][HTML] Integrated analysis of miRNA and mRNA expression profiles in tilapia gonads at an early stage of sex differentiation
W Tao, L Sun, H Shi, Y Cheng, D Jiang, B Fu… - BMC genomics, 2016 - Springer
Background MicroRNAs (miRNAs) represent a second regulatory network that has important
effects on gene expression and protein translation during biological process. However, the …
effects on gene expression and protein translation during biological process. However, the …
Genetics of allergic diseases
RA Ortiz, KC Barnes - Immunology and Allergy Clinics, 2015 - immunology.theclinics.com
Coca and Cooke were the first to describe asthma, atopic dermatitis (AD), allergic rhinitis
(AR), food allergy, and urticaria as “phenomena of hypersensitiveness” at the annual …
(AR), food allergy, and urticaria as “phenomena of hypersensitiveness” at the annual …
[HTML][HTML] Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate
Background To study the role of microRNA (miRNA) in the regulation of Chinese hamster
ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were …
ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were …
Databases for lncRNAs: a comparative evaluation of emerging tools
The vast majority of the human transcriptome does not code for proteins. Advances in
transcriptome arrays and deep sequencing are giving rise to a fast accumulation of large …
transcriptome arrays and deep sequencing are giving rise to a fast accumulation of large …