CTX-M enzymes: origin and diffusion
CTX-M β-lactamases are considered a paradigm in the evolution of a resistance
mechanism. Incorporation of different chromosomal bla CTX-M related genes from different …
mechanism. Incorporation of different chromosomal bla CTX-M related genes from different …
Extended-spectrum β-lactamases: a clinical update
DL Paterson, RA Bonomo - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …
Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat
PA Bradford - Clinical microbiology reviews, 2001 - Am Soc Microbiol
SUMMARY β-Lactamases continue to be the leading cause of resistance to β-lactam
antibiotics among gram-negative bacteria. In recent years there has been an increased …
antibiotics among gram-negative bacteria. In recent years there has been an increased …
Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.
Proteus spp. are commensal Enterobacterales of the human digestive tract. At the same
time, P. mirabilis is commonly involved in urinary tract infections (UTI). P. mirabilis is …
time, P. mirabilis is commonly involved in urinary tract infections (UTI). P. mirabilis is …
Growing group of extended-spectrum β-lactamases: the CTX-M enzymes
R Bonnet - Antimicrobial agents and chemotherapy, 2004 - Am Soc Microbiol
The production of-lactamases is the predominant cause of resistance to-lactam antibiotics in
gram-negative bacteria. These enzymes cleave the amide bond in the-lactam ring …
gram-negative bacteria. These enzymes cleave the amide bond in the-lactam ring …
Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria
WH Zhao, ZQ Hu - Critical reviews in microbiology, 2013 - Taylor & Francis
CTX-M enzymes, the plasmid-mediated cefotaximases, constitute a rapidly growing family of
extended-spectrum β-lactamases (ESBLs) with significant clinical impact. CTX-Ms are found …
extended-spectrum β-lactamases (ESBLs) with significant clinical impact. CTX-Ms are found …
Prevalence and spread of extended‐spectrum β‐lactamase‐producing Enterobacteriaceae in Europe
Extended‐spectrum β‐lactamases (ESBLs) represent a major threat among resistant
bacterial isolates. The first types described were derivatives of the TEM‐1, TEM‐2 and SHV …
bacterial isolates. The first types described were derivatives of the TEM‐1, TEM‐2 and SHV …
β-Lactamases of Kluyvera ascorbata, Probable Progenitors of Some Plasmid-Encoded CTX-M Types
Kluyvera ascorbata produces a β-lactamase that results in an atypical susceptibility pattern,
including low-level resistance to penicillins, cephalothin, and cefuroxime, but this resistance …
including low-level resistance to penicillins, cephalothin, and cefuroxime, but this resistance …
Diversity of CTX-M β-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals
M Saladin, VTB Cao, T Lambert… - FEMS microbiology …, 2002 - academic.oup.com
Nine clinical isolates of Enterobacteriaceae (six Escherichia coli and three Proteus mirabilis)
isolated in three Parisian hospitals between 1989 and 2000 showed a particular extended …
isolated in three Parisian hospitals between 1989 and 2000 showed a particular extended …
Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1
A Karim, L Poirel, S Nagarajan… - FEMS microbiology …, 2001 - academic.oup.com
Six non-clonally related enterobacterial isolates producing a same extended-spectrum β-
lactamase CTX-M-15 were isolated in 1999 from patients hospitalized in a New Delhi …
lactamase CTX-M-15 were isolated in 1999 from patients hospitalized in a New Delhi …