Ischemia–reperfusion–induced lung injury is characterized by nonspecific alveolar damage,
lung edema, and hypoxemia occurring within 72 hours after lung transplantation. The most …

Opening of high conductance permeability transition pores in mitochondria initiates onset of
the mitochondrial permeability transition (MPT). The MPT is a causative event, leading to …

Importance Ischemic cold storage (ICS) of livers for transplant is associated with serious
posttransplant complications and underuse of liver allografts. Objective To determine …

Current organ preservation methods provide a narrow window (usually< 12 hours) to
assess, transport and implant donor grafts for human transplantation. Here we report the …

Liver transplantation is a highly successful treatment, but is severely limited by the shortage
in donor organs. However, many potential donor organs cannot be used; this is because sub …

The ability to preserve metabolically active livers ex vivo for 1 week or more could allow
repair of poor-quality livers that would otherwise be declined for transplantation. Current …

In a retrospective analysis on 323 orthotopic liver transplant procedures performed between
July 1984 and October 1991 the incidence of two forms of primary dysfunction (PDF) of the …

The shortage of organs has led centers to expand their criteria for the acceptance of
marginal donors. The combination of multiple marginal factors seems to be additive on graft …

Based on the findings that the azo functional group has excellent properties as the hypoxia-
sensor moiety, we developed hypoxia-sensitive near-infrared fluorescent probes in which a …

The development of methods to safely preserve organs retrieved from victims of life-ending
accidents greatly improved the versatility of human organ transplantation. In fact, the …