Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Dry eye disease (DED) impacts≈ 30% of the world's population and causes serious ocular
discomfort and even visual impairment. Inflammation is one core cause of the DED vicious …

Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

Iron is an essential component in many biological processes in the human body. It is critical
for the visual phototransduction cascade in the retina. However, excess iron can be toxic …

The eye is a metabolically active structure, constantly exposed to solar radiations making its
structure vulnerable to the high burden of reactive oxygen species (ROS), presenting many …

Highlights•Aging is the major risk factor for AMD.•The macula contains more than 60 kinds of
cells that may age at different rates.•The retinal aging in AMD is determined by its interplay …

Dry eye disease (DED) is a multifactorial disease of the ocular surface system whose chore
mechanisms are tear film instability, inflammation, tear hyperosmolarity and epithelial …

Introduction: There is a limited array of currently available medicinals that are useful for
either the prevention, mitigation or treatment of bodily injuries arising from ionizing radiation …

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is a major factor in the
pathogenesis of dry age-related macular degeneration (AMD). Although the therapeutic …