In low-income and middle-income countries, direct (unconcentrated) sputum smear
microscopy is the primary method for diagnosing pulmonary tuberculosis. The method is …

Objective To assess the magnitude of loss to follow-up in smear-or culture-positive
tuberculosis patients before treatment initiation and outcomes among patients who were …

Summary Background The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect
tuberculosis and its multidrug-resistant form with very high sensitivity and specificity in …

Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low-
And Middle-Income Countries | PLOS Medicine Skip to main content Advertisement PLOS …

Summary Background The Xpert MTB/RIF test for tuberculosis is being rolled out in many
countries, but evidence is lacking regarding its implementation outside laboratories, ability to …

Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid
point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to …

Current international tuberculosis (TB) guidelines recommend the microscopic examination
of three sputum specimens for acid-fast bacilli in the evaluation of persons suspected of …

Tuberculosis is the main cause of morbidity and mortality in people living with HIV/AIDS
worldwide. Early diagnosis and treatment is essential to addressing the dual epidemic of …

Although the human immunodeficiency virus (HIV) infection pandemic has had a
catastrophic impact on tuberculosis (TB) control efforts, especially in sub-Saharan Africa …

The care cascade—which evaluates outcomes across stages of patient engagement in a
health system—is an important framework for assessing quality of tuberculosis (TB) care. In …