Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

The advent of stem cell based therapies has brought regenerative medicine into an
increased focus as a part of the modern medicine practice, with a potential to treat a myriad …

Heterogeneity in cell populations poses a major obstacle to understanding complex
biological processes. Here we present a microfluidic platform containing thousands of …

One of the major branches of microfluidic development is cell engineering. A number of
devices for cell cultivation, lysis, single-cell analysis and cell-based toxicity tests have been …

Stem cells hold great promise as a means of treating otherwise incurable, degenerative
diseases due to their ability both to self-renew and differentiate. However, stem cell damage …

This review examines important robust methods for sustained, steady-state, in vitro culture.
To achieve 'physiologically relevant'tissues in vitro additional complexity must be introduced …

Long-term cell culture in microfluidic devices is an essential prerequisite for “on a chip”
biological and physiological based studies. We investigated how medium delivery, from …

Although stem cell fate is traditionally manipulated by exogenously altering the cells'
extracellular signaling environment, the endogenous autocrine and paracrine signals …

Current techniques used in stem cell research only crudely mimic the physiological
complexity of the stem cell niches. Recent advances in the field of micro-and …

Human pluripotent stem cells (hPSCs) are a promising source of cells for cell replacement-
based therapies as well as modeling human development and diseases in vitro. However …