Peripheral T cell populations are maintained by production of naive T cells in the thymus,
clonal expansion of activated cells, cellular self-renewal (or homeostatic proliferation), and …

Immunological memory—the ability to'remember'previously encountered pathogens and
respond faster on re-exposure—is a central feature of the immune response of vertebrates …

We studied the influence of memory T cell properties on the efficiency of secondary immune
responses by comparing the in vivo immune response of the same numbers of T cell …

In Chance, Development, and Aging, two leading biological gerontologists review and
evaluate all of the available data to elucidate the respective roles played by genes and …

Motivation: Immunological bioinformatics methods are applicable to a broad range of
scientific areas. The specifics of how and where they might be implemented have recently …

Adaptive immunity relies on the generation and maintenance of memory T cells to provide
protection against repeated antigen exposure. It has been hypothesised that a self-renewing …

A central paradigm in the field of lymphocyte biology asserts that replicatively senescent
memory T cells express the carbohydrate epitope CD57. These cells nonetheless …

The human ageing process encompasses mechanisms that effect a decline in homeostasis
with increased susceptibility to disease and the development of chronic life-threatening …

Arstila et al.(1) estimated an average diversity of 9 105 different chains and 4.5 105 different
chains in the human naıve T cell repertoire. To calculate the total T cell repertoire diversity …

It remains uncertain whether full T cell reconstitution can be established in HIV-infected
children and adults with long-term sustained virological control by highly active antiretroviral …