[HTML][HTML] Racial disparity in anthracycline-induced cardiotoxicity in breast cancer patients

S Balaji, AK Antony, H Tonchev, G Scichilone, M Morsy… - Biomedicines, 2023 - mdpi.com
Breast cancer has become the most common cancer in the US and worldwide. While
advances in early detection and treatment have resulted in a 40% reduction in breast cancer …

Cardiovascular Considerations Before Cancer Therapy: Gaps in Evidence and JACC: CardioOncology Expert Panel Recommendations

Z Raisi-Estabragh, AC Murphy, S Ramalingam… - Cardio Oncology, 2024 - jacc.org
Baseline cardiovascular assessment before the initiation of potentially cardiotoxic cancer
therapies is a key component of cardio-oncology, aiming to reduce cardiovascular …

Breast cancer and cardiovascular health

T López-Fernández, I Marco, MC Aznar… - European Heart …, 2024 - academic.oup.com
Modern cancer therapies greatly improve clinical outcomes for both early and advanced
breast cancer patients. However, these advances have raised concerns about potential …

Navigating cancer therapy induced cardiotoxicity: From pathophysiology to treatment innovations

J Tetterton-Kellner, BC Jensen, J Nguyen - Advanced Drug Delivery …, 2024 - Elsevier
Every year, more than a million people in the United States undergo chemotherapy or
radiation therapy for cancer, as estimated by the CDC. While chemotherapy has been an …

Anthracycline-induced cardiovascular toxicity: validation of the Heart Failure Association and International Cardio-Oncology Society risk score

B Rivero-Santana, J Saldaña-García… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Baseline cardiovascular toxicity risk stratification is critical in
cardio-oncology. The Heart Failure Association (HFA) and International Cardio-Oncology …

Prediction of heart failure and all-cause mortality using cardiac ultrasomics in patients with breast cancer

QA Hathaway, Y Abdeen, J Conte, R Hass… - … International Journal of …, 2024 - Springer
Breast cancer chemotherapy/immunotherapy can be associated with treatment-limiting
cardiotoxicity. Radiomics techniques applied to ultrasound, known as ultrasomics, can be …

[HTML][HTML] Artificial intelligence-enhanced risk stratification of cancer therapeutics-related cardiac dysfunction using electrocardiographic images

EK Oikonomou, V Sangha, LS Dhingra, A Aminorroaya… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background: Risk stratification strategies for cancer therapeutics-related cardiac dysfunction
(CTRCD) rely on serial monitoring by specialized imaging, limiting their scalability …

[HTML][HTML] Cardiotoxicity in breast cancer treatment: Causes and mitigation

D Valiyaveettil, D Joseph, M Malik - Cancer Treatment and Research …, 2023 - Elsevier
Survivorship issues and treatment related toxicities have considerably increased in breast
cancer patients following improved therapeutic options. Cardiotoxicity has been a major …

[HTML][HTML] Anthracyclines induce cardiotoxicity through a shared gene expression response signature

ER Matthews, OD Johnson, KJ Horn, JA Gutiérrez… - PLoS …, 2024 - journals.plos.org
TOP2 inhibitors (TOP2i) are effective drugs for breast cancer treatment. However, they can
cause cardiotoxicity in some women. The most widely used TOP2i include anthracyclines …

[HTML][HTML] Neutrophil Biomarkers Can Predict Cardiotoxicity of Anthracyclines in Breast Cancer

VK Todorova, G Azhar, A Stone, SJ Malapati… - International Journal of …, 2024 - mdpi.com
Doxorubicin (DOX), a commonly used anticancer agent, causes cardiotoxicity that begins
with the first dose and may progress to heart failure years after treatment. An inflammatory …