Sulfonamide derivatives are frequently seen structural motifs in medicinal chemistry. Almost
a century after Gerhard Domagk's pioneering work leading to the first sulfonamide antibiotic …

Sulfonamides, with the general formula R-SO2NR1R2, have attracted great attention since
the early discovery of sulfonamide-containing antibacterial drugs. The combinations of …

It is highly desirable to improve charge separation and to provide catalytic functions for the
efficient photocatalytic CO2 reduction reaction (CO2RR) on g-C3N4 (CN). Here, dimension …

Bacterial infections cause substantial morbidity and mortality across the world and pose
serious threats to humankind. Drug resistance, especially multidrug resistance resulting from …

Quinazolinone and quinazoline have been shown different pharmacological activities,
namely anticancer, anti-inflammatory, anti-hyperlipidemia, analgesic, antihypertensive, and …

Background: Many pyrano [2, 3-c] pyrazole derivatives display diverse biological activities
and some of them are known as anticancer, analgesic, anticonvulsant, antimicrobial …

A series of α-aminophosphonates (3a-3m) bearing the sulfisoxazole moiety was synthesized
through one-pot Kabachnik-Fields reaction of sulfisoxazole, diethyl phosphite (DEP) and …

Protein kinases orchestrate diverse cellular functions; however, their dysregulation is linked
to metabolic dysfunctions, associated with many diseases, including cancer. Mitogen …

Abstract The 4‑chloro-6-iodo-2-(4-methoxyphenyl) quinazoline 2 undergoes nucleophilic
substitution with sodium ethoxide followed by the Suzuki–Miyaura reactions to afford novel 6 …

Three quinazolin-4-ylamino derivatives containing phenylbenzenesulfonamides (7a-7c)
were synthesized by reacting (E)-N'-(2-cyanophenyl)-N, N-dimethyl formamidine (6) with …