Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout a man's life and
may have application for treating some cases of male infertility, including those caused by …

The recently developed testis cell transplantation method provides a powerful approach to
studying the biology of the male germline stem cell and its microenvironment, the stem cell …

Spermatogonial stem cells form the foundation of spermatogenesis, and their transplantation
provides a unique opportunity to study spermatogenesis and may offer an alternative …

BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …

OBJECTIVE: To evaluate colonizing ability of human spermatogonial stem cells in mouse
testes. DESIGN: Transplantation of human testis cells into the seminiferous tubules of …

Azoospermia or oligozoospermia due to disruption of spermatogenesis are common causes
of human male infertility. We used the technique of spermatogonial transplantation in two …

Genome editing tools have revolutionized the generation of genetically modified animals
including livestock. In particular, the domestic pig is a proven model of human physiology …

BACKGROUND: Fertility protection is an urgent clinical problem for prepubertal male
oncology patients who undergo either chemotherapy or radiotherapy. As these patients do …