Basal forebrain cholinergic signalling: development, connectivity and roles in cognition
MR Ananth, P Rajebhosale, R Kim… - Nature Reviews …, 2023 - nature.com
Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
mapped the activity and functional connectivity of cholinergic neurons have shown that the …
A multiple hits hypothesis for memory dysfunction in Parkinson disease
S Citro, GD Lazzaro, AT Cimmino, GM Giuffrè… - Nature Reviews …, 2024 - nature.com
Cognitive disorders are increasingly recognized in Parkinson disease (PD), even in early
disease stages, and memory is one of the most affected cognitive domains. Classically …
disease stages, and memory is one of the most affected cognitive domains. Classically …
Cerebral activity manipulation of low-frequency repetitive transcranial magnetic stimulation in post-stroke patients with cognitive impairment
B Yingli, G Zunke, C Wei, W Shiyan - Frontiers in Neurology, 2022 - frontiersin.org
Objective The aim of this study was to evaluate the therapeutic effect of low-frequency
repetitive transcranial magnetic stimulation (rTMS) on post-stroke cognitive impairment …
repetitive transcranial magnetic stimulation (rTMS) on post-stroke cognitive impairment …
M1/M4-Preferring Muscarinic Cholinergic Receptor Agonist Xanomeline Reverses Wake and Arousal Deficits in Nonpathologically Aged Mice
JK Russell, SM Ingram, LB Teal… - ACS Chemical …, 2023 - ACS Publications
Degeneration of the cholinergic basal forebrain is implicated in the development of cognitive
deficits and sleep/wake architecture disturbances in mild cognitive impairment (MCI) and …
deficits and sleep/wake architecture disturbances in mild cognitive impairment (MCI) and …
[HTML][HTML] Longitudinal trajectories of basal forebrain volume in normal aging and Alzheimer's disease
Dysfunction of the cholinergic basal forebrain (BF) system and amyloid-β (Aβ) deposition are
early pathological features in Alzheimer's disease (AD). However, their association in early …
early pathological features in Alzheimer's disease (AD). However, their association in early …
Parkinson's disease cerebrovascular reactivity pattern: A feasibility study
HJ van der Horn, AA Vakhtin, K Julio… - Journal of Cerebral …, 2024 - journals.sagepub.com
A mounting body of research points to cerebrovascular dysfunction as a fundamental
element in the pathophysiology of Parkinson's disease (PD). In the current feasibility study …
element in the pathophysiology of Parkinson's disease (PD). In the current feasibility study …
Abnormal Cerebrovascular Activity, Perfusion, and Glymphatic Clearance in Lewy Body Diseases
Cerebrovascular activity is not only crucial to optimal cerebral perfusion, but also plays an
important role in the glymphatic clearance of interstitial waste, including α‐synuclein. This …
important role in the glymphatic clearance of interstitial waste, including α‐synuclein. This …
Pharmaceutical and pharmacological studies of Shen Ma Yi Zhi granule for prevention of vascular dementia: A review
S Chang, J Liu, H Li, M Liu, D Shi, L Zhou - Frontiers in Neuroscience, 2022 - frontiersin.org
Background: With dementia significantly increasing hospitalization and disability rates,
worldwide aging of the population presents major challenges to public health. The majority …
worldwide aging of the population presents major challenges to public health. The majority …
Sex‐dependent cholinergic effects on amyloid pathology: A translational study
L German‐Castelan, HRC Shanks, R Gros… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION About two‐thirds of Alzheimer's Disease (AD) patients are women, who
exhibit more severe pathology and cognitive decline than men. Whether biological sex …
exhibit more severe pathology and cognitive decline than men. Whether biological sex …
Cortical amyloid burden relates to basal forebrain volume in subjective cognitive decline
Background: Atrophy of cholinergic basal forebrain (BF) nuclei is a frequent finding in
magnetic resonance imaging (MRI) volumetry studies that examined patients with prodromal …
magnetic resonance imaging (MRI) volumetry studies that examined patients with prodromal …