Genetic decoding is not 'frozen'as was earlier thought, but dynamic. One facet of this is
frameshifting that often results in synthesis of a C-terminal region encoded by a new frame …

Bacteria of Shigella spp., the causative agents of shigellosis in humans, possess a
repertoire of∼ 25–30 effectors injected into host cells by a type III secretion apparatus …

Motivation: RNA editing is a phenomenon, which is responsible for the alteration of
particular nucleotides in RNA sequences relative to their genomic templates. Recently, a …

Many Gram‐negative pathogenic bacteria use a type III secretion (T3S) system to interact
with cells of their hosts. Mechanisms controlling the hierarchical addressing of needle …

Transcription fidelity is critical for maintaining the accurate flow of genetic information. The
study of transcription fidelity has been limited because the intrinsic error rate of transcription …

Bacterial genome annotations contain a number of coding sequences (CDSs) that, in spite
of reading frame disruptions, encode a single continuous polypeptide. Such disruptions …

Shigella spp. use a repertoire of virulence plasmid-encoded factors to cause shigellosis.
These include components of a Type III Secretion Apparatus (T3SA) that is required for …

Our goal was to identify evolutionary conserved frame transitions in protein coding regions
and to uncover an underlying functional role of these structural aberrations. We used the ab …

Burkholderia pseudomallei is a highly versatile pathogen capable of infecting many species
of animals and plants. It is the causative agent of melioidosis, a medically important …

Gene regulation involves many different types of transcription control mechanisms, including
mechanisms based on reiterative transcription in which nucleotides are repetitively added to …