Microbioreactor systems for accelerated bioprocess development

J Hemmerich, S Noack, W Wiechert… - Biotechnology …, 2018 - Wiley Online Library
In recent years, microbioreactor (MBR) systems have evolved towards versatile bioprocess
engineering tools. They provide a unique solution to combine higher experimental …

[HTML][HTML] Progress and challenges in large-scale expansion of human pluripotent stem cells

C Kropp, D Massai, R Zweigerdt - Process Biochemistry, 2017 - Elsevier
The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …

minibioreactors

S Kumar, C Wittmann, E Heinzle - Biotechnology Letters, 2004 - Springer
The performance of currently available minibioreactors with volumes below about 100 ml is
reviewed. Bioreactors are characterized by their area of application, by mass transfer and …

Advances in shaking technologies

W Klöckner, J Büchs - Trends in biotechnology, 2012 - cell.com
Shaking bioreactors are the most frequently used reactor system for screening and process
optimization on a small scale. Their success can be attributed to their simple and functional …

Miniature bioreactors: current practices and future opportunities

JI Betts, F Baganz - Microbial cell factories, 2006 - Springer
This review focuses on the emerging field of miniature bioreactors (MBRs), and examines
the way in which they are used to speed up many areas of bioprocessing. MBRs aim to …

Filter paper with selective absorption and separation of liquids that differ in surface tension

S Wang, M Li, Q Lu - ACS Applied Materials & Interfaces, 2010 - ACS Publications
Superhydrophobic and superoleophilic filter paper was successfully prepared by treating
commercially available filter paper with a mixture of hydrophobic silica nanoparticles and …

Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates

F Kensy, E Zang, C Faulhammer, RK Tan… - Microbial cell factories, 2009 - Springer
Background An advanced version of a recently reported high-throughput fermentation
system with online measurement, called BioLector, and its validation is presented. The …

Microbial and enzymatic technologies used for the production of natural aroma compounds: Synthesis, recovery modeling, and bioprocesses

NB Akacha, M Gargouri - Food and Bioproducts Processing, 2015 - Elsevier
This review describes several methodologies of industrial and academic interest which are
implied in the synthesis/extraction of natural aroma compounds by biotechnological …

Microtiter plates as mini-bioreactors: miniaturization of fermentation methods

WA Duetz - Trends in microbiology, 2007 - cell.com
In the past decade, the use of microtiter plates for microbial growth has become widespread,
particularly in industry. In parallel, research in academia has provided a thorough insight …

Membrane‐aerated microbioreactor for high‐throughput bioprocessing

A Zanzotto, N Szita, P Boccazzi… - Biotechnology and …, 2004 - Wiley Online Library
A microbioreactor with a volume of microliters is fabricated out of poly (dimethylsiloxane)(
PDMS) and glass. Aeration of microbial cultures is through a gas‐permeable PDMS …