Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases

M Li, Y Yang, Z Wang, T Zong, X Fu, LHH Aung… - Angiogenesis, 2021 - Springer
Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Increasing
reports demonstrated that non-coding RNAs (ncRNAs) have been crucially involved in the …

[HTML][HTML] Involvement of sirtuins and klotho in cardioprotective effects of exercise training against waterpipe tobacco smoking-induced heart dysfunction

SS Alavi, S Joukar, F Rostamzadeh… - Frontiers in …, 2021 - frontiersin.org
Despite its negative effect on the cardiovascular system, waterpipe smoking (WPS) is
currently popular worldwide, especially among youth. This study investigated the effects of …

SIRT3 attenuates coronary atherosclerosis in diabetic patients by regulating endothelial cell function

H Gong, J Liu, Z Xue, W Wang, C Li… - Journal of Clinical …, 2022 - Wiley Online Library
Background This study aimed to explore the relationship between the Sirtuin 3 (SIRT3) gene
and endothelial cell dysfunction, contributing to the progression of coronary atherosclerosis …

Biomarkers of ageing and cardiac remodeling are associated with atrial fibrillation

AA Kalstad, PL Myhre, K Laake, TB Opstad… - Scandinavian …, 2021 - Taylor & Francis
Objectives. Ageing is one of the strongest risk factors for atrial fibrillation (AF), and additional
risk factors are also closely related to ageing. Remodeling is part of the pathophysiology of …

The serum concentration of anti-aging proteins, sirtuin1 and αKlotho in patients with end-stage kidney disease on maintenance hemodialysis

E Zbroch, A Bazyluk, J Malyszko… - … Interventions in Aging, 2020 - Taylor & Francis
Introduction Sirtuin1 (SIRT1) acts as an anti-aging protein due to anti-apoptotic, anti-
oxidative and anti-inflammatory effect and is implicated in several diseases including …

[HTML][HTML] Biomarkers in cardiovascular disease: The role of fetuin-a

LU Pagan, M Gatto, PF Martinez, K Okoshi… - Arquivos brasileiros de …, 2022 - SciELO Brasil
Cardiovascular disease (CVD) represents a serious health public concern worldwide due to
its high rates of morbidity and mortality. 1 Extensive research has been performed in the …

[HTML][HTML] Differential gene expression patterns in ST-elevation Myocardial Infarction and Non-ST-elevation Myocardial Infarction

M Elahimanesh, N Shokri, E Mahdinia… - Scientific Reports, 2024 - nature.com
Abstract The ST-elevation Myocardial Infarction (STEMI) and Non-ST-elevation Myocardial
Infarction (NSTEMI) might occur because of coronary artery stenosis. The gene biomarkers …

[HTML][HTML] Biomarkers in acute myocardial infarction diagnosis and prognosis

PF Martinez, SA Oliveira-Junior, BF Polegato… - Arquivos brasileiros de …, 2019 - SciELO Brasil
Biomarkers have become a helpful tool for clinicians to establish acute and chronic diseases
diagnosis and prognosis more accurately. The rapid expansion of researches in this field …

Plasma levels of sirtuin-1 in patients with cerebrovascular stroke

IM Esmayel, S Hussein, EA Gohar, HF Ebian… - Neurological …, 2021 - Springer
Abstract Background In Egypt, circulatory system diseases are responsible for one-third of
the annual deaths. Stroke comes 3rd after heart diseases and liver diseases. Stroke …

[HTML][HTML] The Beneficial Effect of the SGLT2 Inhibitor Dapagliflozin in Alleviating Acute Myocardial Infarction-Induced Cardiomyocyte Injury by Increasing the Sirtuin …

YH Lin, WC Tsai, CC Chiu, NY Chi, YH Liu… - International Journal of …, 2024 - mdpi.com
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have a variety of cardiovascular and
renoprotective effects and have been developed as novel agents for the treatment of heart …