[HTML][HTML] Galvanization of protein–protein interactions in a dynamic zinc interactome

A Kocyła, JB Tran, A Krężel - Trends in Biochemical Sciences, 2021 - cell.com
The presence of Zn 2+ at protein–protein interfaces modulates complex function, stability,
and introduces structural flexibility/complexity, chemical selectivity, and reversibility driven in …

Phytochelatins as a dynamic system for Cd (II) buffering from the micro-to femtomolar range

J Wątły, M Łuczkowski, M Padjasek… - Inorganic …, 2021 - ACS Publications
Phytochelatins (PCs) are short Cys-rich peptides with repeating γ-Glu-Cys motifs found in
plants, algae, certain fungi, and worms. Their biosynthesis has been found to be induced by …

Cadmium hijacks the high zinc response by binding and activating the HIZR-1 nuclear receptor

BJ Earley, C Cubillas, K Warnhoff… - Proceedings of the …, 2021 - National Acad Sciences
Cadmium is an environmental pollutant and significant health hazard that is similar to the
physiological metal zinc. In Caenorhabditis elegans, high zinc homeostasis is regulated by …

Mass spectrometry-based structural analysis of cysteine-rich metal-binding sites in proteins with MetaOdysseus R software

MD Peris-Díaz, R Guran, O Zitka, V Adam… - Journal of Proteome …, 2020 - ACS Publications
Identification of metal-binding sites in proteins and understanding metal-coupled protein
folding mechanisms are aspects of high importance for the structure-to-function relationship …

InterMetalDB: a database and browser of intermolecular metal binding sites in macromolecules with structural information

JB Tran, A Krezel - Journal of Proteome Research, 2021 - ACS Publications
InterMetalDB is a free-of-charge database and browser of intermolecular metal binding sites
that are present on the interfaces of macromolecules forming larger assemblies based on …

[HTML][HTML] Влияние кадмия на здоровье населения и способы профилактики его токсических эффектов

АС Фазлыева, РА Даукаев… - Медицина труда и …, 2022 - cyberleninka.ru
Кадмий известный загрязнитель окружающей среды, его негативное воздействие на
человека было и остается серьезной проблемой. Из-за высокой устойчивости металла …

Phytochelatins Bind Zn (II) with Micro-to Picomolar Affinities without the Formation of Binuclear Complexes, Exhibiting Zinc Buffering and Muffling Rather than Storing …

M Łuczkowski, W Leszczyńska, J Wątły… - Inorganic …, 2024 - ACS Publications
Phytochelatins (PCs) are poly-Cys peptides containing a repeating γ-Glu-Cys motif
synthesized in plants, algae, certain fungi, and worms by PC synthase from reduced …

Cadmium exchange with zinc in the non-classical zinc finger protein tristetraprolin

JEP Brandis, SM Zalesak, MA Kane… - Inorganic …, 2021 - ACS Publications
Tristetraprolin (TTP) is a nonclassical CCCH zinc finger protein that regulates inflammation.
TTP targets AU-rich RNA sequences of cytokine mRNAs forming a TTP/mRNA complex. This …

C(P)XCG Proteins of Haloferax volcanii with Predicted Zinc Finger Domains: The Majority Bind Zinc, but Several Do Not

D Üresin, J Schulte, N Morgner, J Soppa - International Journal of …, 2024 - mdpi.com
In recent years, interest in very small proteins (µ-proteins) has increased significantly, and
they were found to fulfill important functions in all prokaryotic and eukaryotic species. The …

Zn(II) to Ag(I) Swap in Rad50 Zinc Hook Domain Leads to Interprotein Complex Disruption through the Formation of Highly Stable Agx(Cys)y Cores

O Kerber, J Tran, A Misiaszek… - Inorganic …, 2023 - ACS Publications
The widespread application of silver nanoparticles in medicinal and daily life products
increases the exposure to Ag (I) of thiol-rich biological environments, which help control the …