Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

Transforming growth factor-β (TGF-β) is the primary factor that drives fibrosis in most, if not
all, forms of chronic kidney disease (CKD). Inhibition of the TGF-β isoform, TGF-β1, or its …

Fibroblast heterogeneity has long been recognized in mouse and human lungs,
homeostasis, and disease states. However, there is no common consensus on fibroblast …

Long noncoding RNAs (lncRNAs) regulate gene expression by association with chromatin,
but how they target chromatin remains poorly understood. We have used chromatin RNA …

The transforming growth factor‐β (TGF‐β) is a family of structurally related proteins that
comprises of TGF‐β, activins/inhibins, and bone morphogenic proteins (BMPs). Members of …

Rationale: Cardiac fibroblasts (CFs) drive extracellular matrix remodeling after pressure
overload, leading to fibrosis and diastolic dysfunction. Recent studies described the role of …

Renal fibrosis is characterized by excessive deposition of extracellular matrix (ECM) that
disrupts and replaces functional parenchyma, which leads to organ failure. It is known as the …

Long noncoding RNAs (lncRNAs) play important roles in various biological processes such
as proliferation, cell death and differentiation. Here, we show that a liver-enriched lncRNA …

Long noncoding RNAs (lncRNAs) have recently considered as central regulators in diverse
biological processes and emerged as vital players controlling tumorigenesis. Several …

Fibrosis is universally observed in multiple aging-related diseases and progressions and is
characterized by excess accumulation of the extracellular matrix. Fibrosis occurs in various …