Atypical antipsychotics (AAP) or second-generation antipsychotics are the clinical option for
schizophrenia treatment during acute psychoses, but they are also indicated for …

Major depressive disorder (MDD) is a highly debilitating condition that is drawing
considerable attention due to its high global prevalence and to the fact that treatments are …

Background Norquetiapine (N-desalkyl quetiapine, NQ) is an active metabolite of quetiapine
with stable pharmacokinetic and pharmacological properties. However, its short half-life is a …

Bentonite (BT) is a biocompatible clay mineral that has advantageous properties as a
pharmaceutical excipient. However, the application of BT in controlled-release oral …

Natural-based drugs are the important bioactive substances, which have been used for
prevention and treatment of diseases. Moreover, several diseases are need to develop the …

Quetiapine is an atypical antipsychotic drug that is widely used for the treatment of
schizophrenia. It is mainly metabolized by a cytochrome P450 system in the liver …

Quetiapine is an atypical antipsychotic drug that can be used to treat mental disorders,
including schizophrenia, bipolar disorder and Alzheimer's disease. Quetiapine is mainly …

Clinical evidence supports the use of second-generation dopamine D2 receptor antagonists
(D2RAs) as adjunctive therapy or in some cases monotherapy in patients with depression …

Background: Recently, pharmaceutical research has focused on in vitro-in vivo correlation
as a novel challenge, and in silico modeling has been an important component. As in silico …

Positive modulation of adult hippocampal neurogenesis may contribute to the therapeutic
effects of clinically relevant antidepressant drugs, including atypical antipsychotics …