Emerging insights into enhancer biology and function
M Arnold, KR Stengel - Transcription, 2023 - Taylor & Francis
Cell type-specific gene expression is coordinated by DNA-encoded enhancers and the
transcription factors (TFs) that bind to them in a sequence-specific manner. As such, these …
transcription factors (TFs) that bind to them in a sequence-specific manner. As such, these …
Transcription factor regulation of ribosomal RNA in hematopoiesis
VR Paralkar - Current Opinion in Hematology, 2024 - journals.lww.com
We propose that a number of hematopoietic transcription factors bind rDNA and potentially
regulate rRNA transcription. Our model has implications for normal and malignant …
regulate rRNA transcription. Our model has implications for normal and malignant …
Chemical-genetics refines transcription factor regulatory circuits
HM Layden, AE Johnson, SW Hiebert - Trends in Cancer, 2024 - cell.com
Transcriptional dysregulation is a key step in oncogenesis, but our understanding of
transcriptional control has relied on genetic approaches that are slow and allow for …
transcriptional control has relied on genetic approaches that are slow and allow for …