Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023 - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

[HTML][HTML] Biological agents for synthesis of nanoparticles and their applications

C Pandit, A Roy, S Ghotekar, A Khusro… - Journal of King Saud …, 2022 - Elsevier
In terms of cost-efficiency, biocompatibility, environmental friendliness, and scalability, green
nanoparticle (NP) synthesis is a novel field of nanotechnology that outperforms both …

Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates

QF Meng, W Tai, M Tian, X Zhuang, Y Pan, J Lai… - Science …, 2023 - science.org
Dexamethasone (DEX) is the first drug to show life-saving efficacy in patients with severe
coronavirus disease 2019 (COVID-19), while DEX is associated with serious adverse …

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation

M Wolf, RW Poupardin, P Ebner‐Peking… - Journal of …, 2022 - Wiley Online Library
Nanoparticles can acquire a plasma protein corona defining their biological identity. Corona
functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we …

[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

G Li, T Chen, J Dahlman… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

Entry and exit of extracellular vesicles to and from the blood circulation

D Iannotta, AW Kijas, AE Rowan, J Wolfram - Nature Nanotechnology, 2024 - nature.com
Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …