Heart failure is a global problem with an estimated prevalence of 38 million patients
worldwide, a number that is increasing with the ageing of the population. It is the most …

Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

Doxorubicin is a highly effective anticancer agent but causes cardiotoxicity in many patients.
The mechanisms of doxorubicin-induced cardiotoxicity remain incompletely understood …

Understanding the phenotypic development of human induced pluripotent stem cell-derived
cardiomyocytes (hiPSC-CMs) is a prerequisite to advancing regenerative cardiac therapy …

Doxorubicin is a highly efficacious anti-cancer drug but causes cardiotoxicity in many
patients. The mechanisms of doxorubicin-induced cardiotoxicity (DIC) remain incompletely …

Chronic heart failure is the end stage of cardiac diseases. With a high prevalence and a high
mortality rate worldwide, chronic heart failure is one of the heaviest health-related burdens …

We report on the development of bioinspired cardiac scaffolds made from electroconductive
acid-modified silk fibroin–poly (pyrrole)(AMSF+ PPy) substrates patterned with nanoscale …

Aging is typified by a gradual loss of physiological fitness and accumulation of cellular
damage, leading to deteriorated functions and enhanced vulnerability to diseases. Antiaging …

Recently, electrospun polyvinylidene fluoride (PVDF) and polyvinylidene fluoride‐
trifluoroethylene (PVDF‐TrFE) scaffolds have been developed for tissue engineering …

The human heart is considered a non-regenerative organ. Worldwide, cardiovascular
diseases continue to be the leading cause of death. Despite advances in cardiac treatment …