The digitisation of health care is offering the promise of transforming the management of
paediatric sepsis, which is a major source of morbidity and mortality in children worldwide …

Sepsis, defined as the life-threatening dysregulated host response to an infection leading to
organ dysfunction, is considered as one of the leading causes of mortality worldwide …

OBJECTIVES: Untangling the heterogeneity of sepsis in children and identifying clinically
relevant phenotypes could lead to the development of targeted therapies. Our aim was to …

Background Although suicide is a leading cause of death among children, the optimal
approach for using health care data sets to detect suicide-related emergencies among …

High ferritin is an important and sensitive biomarker for the various forms of hemophagocytic
lymphohistiocytosis (HLH), a diverse and deadly group of cytokine storm syndromes. Early …

Sepsis contributes to 1 of every 5 deaths globally with 3 million per year occurring in
children. To improve clinical outcomes in pediatric sepsis, it is critical to avoid “one-size-fits …

OBJECTIVES: To use supervised and unsupervised statistical methodology to determine
risk factors associated with mortality in critically ill pediatric oncology patients to identify …

Abstract Background In the United States (US) and in Europe, cystic fibrosis (CF) qualifies as
a rare disease, thus positioning the field to benefit from regulatory incentives provided by …

Background Identifying phenotypes in sepsis patients may enable precision medicine
approaches. However, the generalisability of these phenotypes to specific patient …

Critical illness syndromes including sepsis and acute respiratory distress syndrome (ARDS)
are major causes of morbidity among adults and children admitted to intensive care units …